STING agonist-16|cas:652142-94-4|西域试剂

STING agonist-16,98.58%

产品编号：Bellancom-131994| CAS NO：652142-94-4| 分子式：C₁₉H₁₁Cl₂N₅O| 分子量：396.23

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货号	包装	价格	库存与货期	购买量	操作
Bellancom-131994		￥1000.00	杭州北京（现货）
Bellancom-131994		￥3000.00	杭州北京（现货）

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STING agonist-16

产品介绍

STING agonist-16 (1a) 是一种特异性的干扰素基因刺激物 (STING) 激动剂。STING agonist-16 (1a) 可用于抗病毒和抗肿瘤的潜在工具。

生物活性

STING agonist-16 (1a) is a specific stimulator of interferon genes (STING) agonist. STING agonist-16 (1a) can be used as a potential antiviral and antitumor tool.

体外研究

STING agonist-16 (1a) (0-100 μM, 6 h) can promote mRNA expression of IFNβ, CXCL-10 and IL-6 in a dose-dependent manner with no significant cytotoxic effect up to 100 μM in human myeloid leukemia mononuclear cells (THP1).
STING agonist-16 (1a) (50 μM, 2 h) significantly induces the phosphorylation of STING, TANK-binding kinases1 (TBK1) and interferon regulatory factor 3 (IRF3) in THP1 cells.
STING agonist-16 (1a) activates secretory alkaline phosphatase (SEAP) in a dose-dependent manner with an EC₅₀ value of 16.77 μM while 2'3'-cGAMP acts with an EC₅₀ value of 9.212 μM.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

性状

Solid

溶解性数据

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式