PSI-7976|cas:1190308-01-0|西域试剂

PSI-7976,98.24%

产品编号：Bellancom-15005A| CAS NO：1190308-01-0| 分子式：C₂₂H₂₉FN₃O₉P| 分子量：529.45

PSI-7976是PSI-7977(HY-15005)的同分异构体，能抑制HCV RNA复制，EC50为1.07uM。

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货号	包装	价格	库存与货期	购买量	操作
Bellancom-15005A		￥4200.00	杭州北京（现货）
Bellancom-15005A		￥9800.00	杭州北京（现货）

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PSI-7976

产品介绍

PSI-7976是PSI-7977(HY-15005)的同分异构体，能抑制HCV RNA复制，EC50为1.07uM。

生物活性

PSI-7976 is the isomer of PSI-7977. PSI-7977 is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity.

体外研究

PSI-7851 is a mixture of two diastereoisomers, PSI-7976 and PSI-7977, with PSI-7977 being the more active inhibitor of HCV RNA replication in the HCV replicon assay. Carboxylesterase 1 (CES1) preferentially hydrolyzes PSI-7976 over PSI-7977. The kinetic data also indicates that PSI-7976 is a better substrate for CES1 than for cathepsin A (CatA)

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

性状

Solid

溶解性数据

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

参考文献

. Murakami E, et al. Mechanism of activation of PSI-7851 and its diastereoisomer PSI-7977. J Biol Chem. 2010 Nov 5;285(45):34337-47. [Content Brief]

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产品编号(Item Number)

批号(Lot Number)

PSI-7976,98.24%

PSI-7976

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