Tunicamycin V Tunicamycin A,95.0%
产品编号:Bellancom-N8395| CAS NO:66054-36-2| 分子式:C39H64N4O16| 分子量:844.94
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Tunicamycin V Tunicamycin A
产品介绍 | Tunicamycin V (Tunicamycin A) 是一种核苷天然产物,可抑制细菌 phospho-N-acetylmuramyl-pentapeptide transferase (MraY),IC50 为 0.35 μM。Tunicamycin V 具有抗菌活性。 | |||||||||
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生物活性 | Tunicamycin V (Tunicamycin A) is a nucleoside natural product that inhibits bacterial phospho-N-acetylmuramyl-pentapeptide transferase (MraY) with an IC50 of 0.35 μM. Tunicamycin V has antibacterial activties. | |||||||||
体外研究 |
Tunicamycins are nucleoside natural products isolated from the fermentation broths of Streptomyces lysosuperficus in 1971 and exhibit a variety of biological properties including antibacterial, antiviral, antifungal, and antitumor activities. Tunicamycins strongly inhibit UDP-N-acetylglucosamine (GlcNAc): polyprenol phosphate translocase, the enzyme responsible for the first N-acetylglucosamination of the N-linked glycopeptide in endothelial reticulum (ER). 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | |||||||||
体内研究 | ||||||||||
体内研究 | ||||||||||
性状 | Solid | |||||||||
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运输条件 | Room temperature in continental US; may vary elsewhere. | |||||||||
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