Cbl-b-IN-3
产品编号：Bellancom-141432| CAS NO：2573775-59-2| 分子式：C30H34F3N5O| 分子量：537.62
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Cbl-b-IN-3
| 产品介绍 | Cbl-b-IN-3 (Compound 23) 是 casitas B 系淋巴瘤原癌基因-b (Cbl-b) 抑制剂， IC50 为 < 1 nM。 Cbl-b 是一种 E3 泛素连接酶，负调控 T 细胞活化。 |
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| 生物活性 | Cbl-b-IN-3 (Compound 23) is a casitas B-lineage lymphoma proto-oncogene-b (Cbl-b) inhibitor with an IC50 of < 1 nM. Cbl-b is an E3 ubiquitin ligase that negatively regulates T-cell activation. |
| 体外研究 |
Cbl-b-IN-3 (Compound 23) enhances IL-2 secretion by T-cells stimulated with an anti-CD3 antibody alone or in combination with an anti-CD28 antibody. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. |
| 体内研究 | |
| 体内研究 | |
| 性状 | Solid |
| 溶解性数据 | |
| 运输条件 | Room temperature in continental US; may vary elsewhere. |
| 储存方式 |
4°C, sealed storage, away from moisture and light *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
| 参考文献 |
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