嘧霉胺|Pyrimethanil |cas:53112-28-0|西域试剂

嘧霉胺,Pyrimethanil ,优级纯,99.83%

产品编号：西域试剂-B2033| CAS NO：53112-28-0| 分子式：C₁₂H₁₃N₃| 分子量：199.25

Pyrimethanil 是一种苯胺嘧啶类广谱接触杀菌剂 (fungicide)，用于控制多种作物上 Botrytis spp.。Pyrimethanil 抑制灰霉病菌中蛋氨酸和其他氨基酸的生物合成。Pyrimethanil 可用于霉菌感染的水果、蔬菜和观赏植物真菌病害防治的相关研究。

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货号	包装	价格	库存与货期	购买量	操作
西域试剂-B2033		￥650.00	杭州北京（现货）

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产品名称

嘧霉胺

英文名称

Pyrimethanil

CAS编号

53112-28-0

产品描述

产品熔点

96°C

产品沸点

362.8±45.0 °C at 760 mmHg

产品密度

1.1±0.1 g/cm3

产品闪点

173.2±28.7 °C

精确质量

199.110947

PSA

37.81000

LogP

2.84

外观性状

淡黄色晶体粉末

蒸气压

0.0±0.8 mmHg at 25°C

折射率

1.622

溶解性

0.121 g/L (25 ºC)

溶解性数据

In Vitro:

DMSO : 130 mg/mL (652.45 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	5.0188 mL	25.0941 mL	50.1882 mL
5 mM	1.0038 mL	5.0188 mL	10.0376 mL
10 mM	0.5019 mL	2.5094 mL	5.0188 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用；以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

1.

请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% saline
Solubility: ≥ 3.25 mg/mL (16.31 mM); Clear solution

此方案可获得 ≥ 3.25 mg/mL (16.31 mM，饱和度未知) 的澄清溶液。
以 1 mL 工作液为例，取 100 μL 32.5 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中，混合均匀；向上述体系中加入50 μL Tween-80，混合均匀；然后继续加入 450 μL生理盐水定容至 1 mL。
将 0.9 g 氯化钠，完全溶解于 100 mL ddH₂O 中，得到澄清透明的生理盐水溶液
2.

请依序添加每种溶剂： 10% DMSO 90% (20% SBE-β-CD in saline)
Solubility: 3.25 mg/mL (16.31 mM); Suspended solution; Need ultrasonic

此方案可获得 3.25 mg/mL (16.31 mM) 的均匀悬浊液，悬浊液可用于口服和腹腔注射。
以 1 mL 工作液为例，取 100 μL 32.5 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中，混合均匀。
将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中，再用生理盐水定容至 10 mL，完全溶解，澄清透明
3.

请依序添加每种溶剂： 10% DMSO 90% corn oil
Solubility: ≥ 3.25 mg/mL (16.31 mM); Clear solution

此方案可获得 ≥ 3.25 mg/mL (16.31 mM，饱和度未知) 的澄清溶液，此方案不适用于实验周期在半个月以上的实验。
以 1 mL 工作液为例，取 100 μL 32.5 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中，混合均匀。

*以上所有助溶剂都可在西域网站选购。

体外研究

乙胺嘧啶是一种菊酯类杀菌剂。乙胺嘧啶（5和50 µg/L）引起一系列毒性反应，有可能引起意大利树蛙组织的组织学改变 H。长期暴露于两种环境相关浓度的乙胺嘧啶后的中间产物。乙胺嘧啶降低了三天龄培养基中多聚半乳糖醛酸酶、纤维素酶、蛋白酶和漆酶的活性。乙胺嘧啶使总酶活性降低50%（IC50）约为0.25μM表示多聚半乳糖醛酸酶、纤维素酶和蛋白酶，约为1.0μM代表漆酶。

稳定性

如果遵照规格使用和储存则不会分解，未有已知危险反应

储存条件

密封、在 0-6 ºC下保存

化学品安全说明书(MSDS)

下载MSDS

质检证书(COA)

相关产品

符号	GHS09
危害声明	H411
警示性声明	P273
个人防护装备	dust mask type N95 (US);Eyeshields;Gloves
危害码 (欧洲)	N:Dangerousfortheenvironment;
风险声明 (欧洲)	R51/53
安全声明 (欧洲)	S60
危险品运输编码	UN 3077
海关编码	2942000000

Material Safety Data Sheet

Section1. Identiﬁcation of the substance
Product Name: Pyrimethanil
Synonyms:

Section2. Hazards identiﬁcation
Harmful by inhalation, in contact with skin, and if swallowed.

Section3. Composition/information on ingredients.
Ingredient name:Pyrimethanil
CAS number:53112-28-0

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
ﬂushing of the eyes by separating the eyelids with ﬁngers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire ﬁghting measures
In the event of a ﬁre involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualiﬁed
in the handling and use of potentially hazardous chemicals, who should take into account the ﬁre,
health and chemical hazard data given on this sheet.
Store in closed vessels.
Storage:

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not speciﬁed
Boiling point:No data
No data
Melting point:
Flash point:No data
Density:No data
Molecular formula:C12H13N3
Molecular weight:199.3

Section10. Stability and reactivity
Conditions to avoid: Heat, ﬂames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, nitrogen oxides.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
Non-harzardous for air and ground transportation.

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.

SECTION 16 - ADDITIONAL INFORMATION
N/A