(S)-Mapracorat (S-ZK-245186; (S)-BOL-303242X)|cas:887375-15-7|西域试剂

(S)-Mapracorat (S-ZK-245186; (S)-BOL-303242X),99.40%

产品编号：Bellancom-14864A| CAS NO：887375-15-7| 分子式：C₂₅H₂₆F₄N₂O₂| 分子量：462.48

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货号	包装	价格	库存与货期	购买量	操作
Bellancom-14864A		￥6500.00	杭州北京（现货）
Bellancom-14864A		￥9500.00	杭州北京（现货）

增值税发票√顺丰快递√订货电话：18601927057

(S)-Mapracorat (S-ZK-245186; (S)-BOL-303242X)

产品介绍

(S)-Mapracorat 是一种选择性且活性较小的糖皮质激素受体激动剂。

生物活性

(S)-Mapracorat is a selective and less active glucocorticoid receptor agonist.

体外研究

(S)-Mapracorat concentration dependently inhibited TNFα secretion from activated canine PBMC with IC₅₀ value of approximately 0.2 nM.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

Intradermal injection of compound 48/80 (50 μg in 50 μL saline) resulted in a clear wheal and flare reaction over the 60 min observation period. Topical pre-treatment with (S)-Mapracorat (0.1%) leads to significant reduction in the wheal and flare responses compared to vehicle (acetone) treated areas.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

性状

Solid

溶解性数据

In Vitro:

DMSO : ≥ 50.6 mg/mL (109.41 mM)

* "≥" means soluble, but saturation unknown.

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	2.1623 mL	10.8113 mL	21.6226 mL
5 mM	0.4325 mL	2.1623 mL	4.3245 mL
10 mM	0.2162 mL	1.0811 mL	2.1623 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式