Human growth hormone-releasing factor Growth Hormone Releasing Factor human|cas:83930-13-6|西域试剂

Human growth hormone-releasing factor Growth Hormone Releasing Factor human

产品编号：Bellancom-P0089| CAS NO：83930-13-6| 分子式：C₂₁₅H₃₅₈N₇₂O₆₆S| 分子量：5039.65

Human growth hormone-releasing factor 通过与脑垂体前细胞生长激素释放激素受体 (GHRHR) 结合，从而刺激生长激素的生成和释放。

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货号	价格	库存与货期
Bellancom-P0089	￥1500.00	杭州北京（现货）
Bellancom-P0089	￥2200.00	杭州北京（现货）
Bellancom-P0089	￥7700.00	杭州北京（现货）
Bellancom-P0089	￥12000.00	杭州北京（现货）

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Human growth hormone-releasing factor Growth Hormone Releasing Factor human

产品介绍

Human growth hormone-releasing factor (Growth Hormone Releasing Factor human) 是一种下丘脑多肽，通过与脑垂体前细胞生长激素释放激素受体 (GHRHR) 结合，从而刺激生长激素的生成和释放。

生物活性

Human growth hormone-releasing factor (Growth Hormone Releasing Factor human) is a hypothalamic polypeptide and stimulates GH production and release by binding to the GHRH Receptor (GHRHR) on cells in the anterior pituitary.

体外研究

The GHRHR is a member of the class II B GPCR family, which couples predominantly to the Gs-adenylate cyclase-cAMP signaling pathway. Peptide hormones that activate class II GPCRs include GHRH, secretin, glucagon-like peptides, gastric-inhibitory peptide (GIP), pituitary adenylate cyclase-activating peptide, corticotropin-releasing hormone, vasoactive intestinal peptide, parathyroid hormone, and calcitonin-related peptides.
GHRH, expressed in the arcuate nucleus of the hypothalamus and released into portal vasculature, directly stimulates growth hormone synthesis and secretion from the pituitary somatotropes by activating the corresponding GHRH receptors.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

性状

Solid

溶解性数据

In Vitro:

H₂O : 25 mg/mL (4.96 mM; Need ultrasonic and warming)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	0.1984 mL	0.9921 mL	1.9843 mL
5 mM	---	---	---
10 mM	---	---	---

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

参考文献

. Fridlyand LE, et al.Growth Hormone-Releasing Hormone in Diabetes.Front Endocrinol (Lausanne). 2016 Oct 10;7:129. eCollection 2016. [Content Brief]

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产品编号(Item Number)

批号(Lot Number)

个人防护装备	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
危险品运输编码	NONH for all modes of transport
WGK德国	3

Human growth hormone-releasing factor Growth Hormone Releasing Factor human

Human growth hormone-releasing factor Growth Hormone Releasing Factor human

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