RS100329 hydrochloride,99.57%
产品编号：Bellancom-103204| CAS NO：1215654-26-4| 分子式：C20H26ClF3N4O3| 分子量：462.89
本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用，
RS100329 hydrochloride
| 产品介绍 | RS100329 hydrochloride 是一种有效的选择性 α1A-肾上腺素能受体拮抗剂，拮抗 α1A、 α1D 和 α1B 的 pKi 值分别为 9.6、7.9 和 7.5。RS100329 hydrochloride 对反射性尿道收缩有抑制作用。RS100329 hydrochloride 可用于良性前列腺增生的研究。 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 生物活性 | RS100329 hydrochloride is a potent and selective α1A-adrenoceptor antagonist with pKi values of 9.6, 7.9 and 7.5 for α1A, α1D, and α1B, respectively. RS100329 hydrochloride inhibits reflex urethral contractions. RS100329 hydrochloride can be used in research of benign prostatic hyperplasia. | ||||||||
| 体外研究 |
RS100329 hydrochloride (human lower urinary tract (LUT) tissues) contractions to Norepinephrine (HY-13715) is antagonized in a surmountable and concentration-dependent manner. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||
| 体内研究 |
RS100329 hydrochloride (0.01-0.1 mg/kg; i.v.; Sprague Dawley rats) reduces baseline urethral pressure and inhibit reflex urethral contractions. 西域 has not independently confirmed the accuracy of these methods. They are for reference only.
| ||||||||
| 体内研究 |
RS100329 hydrochloride (0.01-0.1 mg/kg; i.v.; Sprague Dawley rats) reduces baseline urethral pressure and inhibit reflex urethral contractions. 西域 has not independently confirmed the accuracy of these methods. They are for reference only.
| ||||||||
| 性状 | Solid | ||||||||
| 溶解性数据 | |||||||||
| 运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
| 储存方式 |
4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) | ||||||||
| 参考文献 |
|
浙公网安备 33010802013016号