18-Oxocortisol,98.0%
产品编号：Bellancom-113151| CAS NO：2410-60-8| 分子式：C21H28O6| 分子量：376.44
本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用，
18-Oxocortisol
| 产品介绍 | 18-Oxocortisol 是由醛固酮合酶 (CYP11B2) 产生的皮质醇衍生物。18-Oxocortisol 是天然存在的盐皮质激素 (mineralocorticoid) 激动剂。18-Oxocortisol 是肾上腺静脉采样中的生物标志物。 | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 生物活性 | 18-Oxocortisol is a derivative of cortisol that is produced by aldosterone synthase (CYP11B2). 18-Oxocortisol is a naturally occurring mineralocorticoid agonist. 18-Oxocortisol is a biomarker in adrenal vein sampling. | ||||||||||||
| 体外研究 | |||||||||||||
| 体内研究 |
Administration of 18-oxocortisol to rats induces a mineralocorticoid-type hypertension with hypokalemia, cardiac and renal enlargement and cardiovascular lesions. Administration of 18-oxocortisol to sheep also causes a rapid increase in blood pressure. However, the doses required for increasing blood pressure are high. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||||||
| 体内研究 |
Administration of 18-oxocortisol to rats induces a mineralocorticoid-type hypertension with hypokalemia, cardiac and renal enlargement and cardiovascular lesions. Administration of 18-oxocortisol to sheep also causes a rapid increase in blood pressure. However, the doses required for increasing blood pressure are high. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||||||
| 性状 | Solid | ||||||||||||
| 溶解性数据 | |||||||||||||
| 运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| 储存方式 |
| ||||||||||||
| 参考文献 |
|
浙公网安备 33010802013016号