CGP 20712 A CGP 20712 mesylate|cas:105737-62-0|西域试剂

CGP 20712 A CGP 20712 mesylate

产品编号：Bellancom-101355B| CAS NO：105737-62-0| 分子式：C₂₄H₂₉F₃N₄O₈S| 分子量：590.57

本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用，

货号	包装	价格	库存与货期	购买量	操作
Bellancom-101355B		￥5600.00	杭州北京（现货）
Bellancom-101355B		￥9500.00	杭州北京（现货）

增值税发票√顺丰快递√订货电话：18601927057

CGP 20712 A CGP 20712 mesylate

产品介绍

CGP 20712 A (CGP 20712 mesylate) 是一种高选择性 β1-adrenoceptor 拮抗剂，IC₅₀ 为 0.7 nM，是对 β2 肾上腺素受体的选择性约为 10,000 倍。

生物活性

CGP 20712 A (CGP 20712 mesylate) is a highly selective β1-adrenoceptor antagonist with an IC₅₀ of 0.7 nM. CGP 20712 A exhibits ~10,000-fold selectivity over β2-adrenoceptors.

体外研究

In myocytes, the activation of adenylate cyclase causes by β2-adrenoceptors is not detected in the presence of 10 nM, 100 nM or 1000 nM CGP 20712 A (CGP 20712 mesylate), which selectively antagonized beta1-adrenoceptors.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

Pretreatment of 8-day-old rats with 5 mg/kg CGP 20712 A do not change the plasma ACTH response to insulin injection.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

Pretreatment of 8-day-old rats with 5 mg/kg CGP 20712 A do not change the plasma ACTH response to insulin injection.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

性状

Solid

溶解性数据

In Vitro:

DMSO : 100 mg/mL (169.33 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	1.6933 mL	8.4664 mL	16.9328 mL
5 mM	0.3387 mL	1.6933 mL	3.3866 mL
10 mM	0.1693 mL	0.8466 mL	1.6933 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

参考文献