CC-90002 is a humanized anti-CD47 monoclonal antibody (mAb). CC-90002 has a high affinity for binding to CD47 with a subnanomolar K_d value. CC-90002 can be used for the research of hematologic malignancies and solid tumors.

CC-90002 has a high affinity for binding to CD47 with a subnanomolar dissociation constant (K_d) value.
CC-90002 can block the CD47-SIRPa interaction with IC₅₀ value in the subnanomolar range.
CC-90002 has inhibitory effect in concentration-dependent in the ALL and AML cell lines.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

CC-90002 shows significant dose-dependent antitumor activity and significant tumor regression in tumor xenografts models.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

CC-90002 shows significant dose-dependent antitumor activity and significant tumor regression in tumor xenografts models.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

• . Rama Krishna Narla, et al. The humanized anti-CD47 monclonal antibody, CC-90002, has antitumor activity in vitro and in vivo.

  . Zhongxing Jiang, et al. Targeting CD47 for cancer immunotherapy. J Hematol Oncol. 2021 Oct 30;14(1):180.  [Content Brief]