Darinaparsin ZIO-101; S-Dimethylarsino-glutathione,98.0%
产品编号：Bellancom-14943| CAS NO：69819-86-9| 分子式：C12H22AsN3O6S| 分子量：411.31
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Darinaparsin ZIO-101; S-Dimethylarsino-glutathione
| 产品介绍 | Darinaparsin (ZIO-101) 是一种有机砷，是一种线粒体靶向剂。Darinaparsin 可诱导癌细胞凋亡 (apoptosis)，并具有抗癌作用。 | |||||||||
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| 生物活性 | Darinaparsin (ZIO-101), an organic arsenical, is a mitochondrial-targeted agent. Darinaparsin induces apoptosis in ancer cells, and has anticancer effects. | |||||||||
| 体外研究 |
Darinaparsin is cytotoxic to prostate cancer cell lines as well as fresh prostate cancer cells at low micromolar concentrations, and importantly inhibits the termed tumor-initiating cells (TIC) subpopulations. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | |||||||||
| 体内研究 |
Darinaparsin inhibits growth of the castrate-resistant Du145 prostate tumor propagated as xenograft in mice and inhibits the tumor-initiating potential of prostate cancer cells. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | |||||||||
| 体内研究 |
Darinaparsin inhibits growth of the castrate-resistant Du145 prostate tumor propagated as xenograft in mice and inhibits the tumor-initiating potential of prostate cancer cells. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | |||||||||
| 性状 | Solid | |||||||||
| 溶解性数据 | ||||||||||
| 运输条件 | Room temperature in continental US; may vary elsewhere. | |||||||||
| 储存方式 |
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| 参考文献 |
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