Maytansinoid B
产品编号：Bellancom-148870| CAS NO：1628543-40-7| 分子式：C36H51ClN4O10| 分子量：735.26
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Maytansinoid B
| 产品介绍 | Maytansinoid B 是一种 ADC Cytotoxin，能够与抗体耦连形成 Antibody-Drug Conjugates (ADCs)。Maytansinoids 是已知的抗有丝分裂剂，与微管蛋白结合并抑制微管组装。Maytansinoids 可诱导细胞周期在 G2/M 阻滞，从而诱导细胞凋亡 (apoptosis)。 | ||||||||||||
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| 生物活性 | Maytansinoid B is a kind of ADC Cytotoxin. Maytansinoid B can be used to conjugates with antibodies to form antibody-drug conjugates (ADCs). Maytansinoids are known as antimitotic agents, binding to tubulin and inhibiting microtubule assembly. Maytansinoids induces G2/M arrest in the cell cycle to induce apoptosis. | ||||||||||||
| 体外研究 |
Maytansinoid 对包括淋巴瘤系在内的几种肿瘤细胞系表现出 10-90 pM 的细胞毒活性。 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||||||
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| 性状 | Solid | ||||||||||||
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| 运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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