PMEDAP|cas:113852-41-8|西域试剂

PMEDAP,98.0%

产品编号：Bellancom-106382| CAS NO：113852-41-8| 分子式：C₈H₁₃N₆O₄P| 分子量：288.20

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货号	价格	库存与货期
Bellancom-106382	￥1500.00	杭州北京（现货）
Bellancom-106382	￥2500.00	杭州北京（现货）
Bellancom-106382	￥5500.00	杭州北京（现货）
Bellancom-106382	￥9500.00	杭州北京（现货）

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PMEDAP

产品介绍

PMEDAP 是人类免疫缺陷病毒 (HIV) 复制的有效抑制剂。PMEDAP 具有抗小鼠巨细胞病毒 (MCMV) 活性。PMEDAP 是莫罗尼鼠肉瘤病毒 (MSV) 诱导的肿瘤形成和相关死亡率的有效抑制剂。

生物活性

PMEDAP is a potent inhibitor of human immunodeficiency virus (HIV) replication. PMEDAP has anti-murine cytomegalovirus (MCMV) activity. PMEDAP is a very potent inhibitor of Moloney murine sarcoma virus (MSV)-induced tumor formation and associated mortality.

体外研究

体内研究

PMEDAP (0.25-5 mg/kg; IP; daily; starting on the day of MSV-infected and continuing for an additional four days) causes a dose-dependent suppression of tumor formation and mortality in newborn mice inoculated with MSV.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Three-week-old male NMRI mice
Dosage:	0.25 mg/kg, 1 mg/kg, 5 mg/kg
Administration:	IP; daily; starting on the day of infection and continuing for an additional four days
Result:	Effected a significant delay in tumor appearance and an enhancement of the survival rate of tumor-bearing mice.

体内研究

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Three-week-old male NMRI mice
Dosage:	0.25 mg/kg, 1 mg/kg, 5 mg/kg
Administration:	IP; daily; starting on the day of infection and continuing for an additional four days
Result:	Effected a significant delay in tumor appearance and an enhancement of the survival rate of tumor-bearing mice.

性状

Solid

溶解性数据

In Vitro:

0.1 M NaOH : 14.29 mg/mL (49.58 mM; ultrasonic and adjust pH to 12 with NaOH)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	3.4698 mL	17.3491 mL	34.6981 mL
5 mM	0.6940 mL	3.4698 mL	6.9396 mL
10 mM	0.3470 mL	1.7349 mL	3.4698 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

参考文献