(E/Z)-Eltrombopag-13C4 (E/Z-SB-497115-13C4),97.0%
产品编号：Bellancom-15306S| CAS NO：1217230-31-3| 分子式：C2113C4H22N4O4| 分子量：446.44
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(E/Z)-Eltrombopag-13C4 (E/Z-SB-497115-13C4)
| 产品介绍 | (E/Z)-Eltrombopag-13C4 是 E-Eltrombopag 与 Z-Eltrombopag 异构体的混合物，带有 13C 标记。Z-Eltrombopag 是一种具有口服活性的 thrombopoietin-receptor 非肽激动剂。Eltrombopag 可促血小板的活性，用于治疗血小板计数低的慢性免疫性血小板减少症。Eltrombopag 可用于心血管的研究。Eltrombopag 对多药耐药的金黄色葡萄球菌 (Staphylococcus aureus) 也有很强的抑制作用。Eltrombopag 还可诱导肝癌细胞凋亡 (apoptosis)。 | ||||||||||||
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| 生物活性 | (E/Z)-Eltrombopag-13C4 is a mixture complex of E-Eltrombopag and Z-Eltrombopag, with 13C labeled. Z-Eltrombopag is an orally active thrombopoietin receptor nonpeptide agonist. Eltrombopag owns thrombopoietic activity, and has been used to research low blood platelet counts with chronic immune thrombocytopenia. Eltrombopag can be used for the research of cardiovascular. Eltrombopag also has highly inhibitory effects against multidrug resistant Staphylococcus aureus. Eltrombopag can induce apoptosis in hepatocellular carcinomab (HCC) as well[4][5]. | ||||||||||||
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| 性状 | Solid | ||||||||||||
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| 运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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