Aspirin-d3 Acetylsalicylic Acid-d3; ASA-d3|cas:921943-73-9|西域试剂

Aspirin-d₃ Acetylsalicylic Acid-d₃; ASA-d₃,98.0%

产品编号：Bellancom-14654S| CAS NO：921943-73-9| 分子式：C₉H₅D₃O₄| 分子量：183.18

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Aspirin-d₃ Acetylsalicylic Acid-d₃; ASA-d₃

产品介绍

Aspirin-d₃ 是 Aspirin 的氘代物。Aspirin是非选择性和不可逆的 COX-1 和 COX-2 抑制剂，IC₅₀ 分别为5，210 μg/mL。

生物活性

Aspirin-d₃ is the deuterium labeled Aspirin. Aspirin is a non-selective and irreversible inhibitor of COX-1 and COX-2 with IC50s of 5 and 210 μg/mL.

体外研究

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

性状

Solid

溶解性数据

In Vitro:

DMSO : 100 mg/mL (545.91 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	5.4591 mL	27.2956 mL	54.5911 mL
5 mM	1.0918 mL	5.4591 mL	10.9182 mL
10 mM	0.5459 mL	2.7296 mL	5.4591 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式