Niclosamide-13C6 BAY2353-13C6,99.0%
产品编号:Bellancom-B0497S1| CAS NO:1325808-64-7| 分子式:C713C6H8Cl2N2O4| 分子量:333.08
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Niclosamide-13C6 BAY2353-13C6
产品介绍 | Niclosamide-13C6 是 13C6 标记的 Niclosamide。Niclosamide (BAY2353) 是一种口服生物可利用的氯化水杨酰苯胺,具有驱虫和潜在的抗肿瘤活性。 Niclosamide (BAY2353) 可抑制 STAT3,在 HeLa 细胞中 IC50 0.25 μM,并在无细胞试验中抑制 DNA 复制。 | ||||||||||||
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生物活性 | Niclosamide-13C6 is the 13C6 labeled Niclosamide. Niclosamide (BAY2353) is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Niclosamide (BAY2353) inhibits STAT3 with IC50 of 0.25 μM in HeLa cells and inhibits DNA replication in a cell-free assay. | ||||||||||||
体外研究 |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||||||
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性状 | Solid | ||||||||||||
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运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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