TDP1 Inhibitor-2,99.84%
产品编号：Bellancom-147750| CAS NO：859142-95-3| 分子式：C25H14Cl2O5| 分子量：465.28
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TDP1 Inhibitor-2
| 产品介绍 | TDP1 Inhibitor-2 (化合物 5) 是一种有效的 TDP1 (酪氨酰 -DNA 磷酸二酯酶 1) 抑制剂，其 IC50 为99 nM。TDP1 Inhibitor-2 也可抑制 SCAN1 (脊髓小脑共济失调综合征伴轴突神经病变)，其 IC50 为 3.5 μM. | ||||||||||||
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| 生物活性 | TDP1 Inhibitor-2 (compound 5) is a potent inhibitor for TDP1 (tyrosyl-DNA phosphodiesterase 1), with an IC50 of 99 nM. TDP1 Inhibitor-2 also can inhibit SCAN1 (spinocerebellar ataxia syndrome with axonal neuropathy), with an IC50 of 3.5 μM. | ||||||||||||
| 体外研究 |
TDP1 Inhibitor-2 (compound 5) shows potent anti-TDP1 activity, low cytotoxicity and synergism with topotecan, an established Top1 anticancer agent. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||||||
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| 性状 | Solid | ||||||||||||
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| 运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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