Propargyl-PEG8-NHS ester
产品编号：Bellancom-130376| CAS NO：2182601-74-5| 分子式：C24H39NO12| 分子量：533.57
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Propargyl-PEG8-NHS ester
| 产品介绍 | Propargyl-PEG8-NHS ester 是一种 PROTAC 连接桥，属于 PEG 类和 Alkyl/ether 类。Propargyl-PEG8-NHS ester 可用于合成一系列 PROTAC 分子。Propargyl-PEG8-NHS ester 是一种可降解 (cleavable) 的 ADC 连接桥，用于抗体活性分子结合物 (ADCs) 的合成。 | |||||||||
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| 生物活性 | Propargyl-PEG8-NHS ester is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG8-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | |||||||||
| 体外研究 |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | |||||||||
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| 性状 | Viscous liquid | |||||||||
| 溶解性数据 | ||||||||||
| 运输条件 | Room temperature in continental US; may vary elsewhere. | |||||||||
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| 参考文献 |
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