(E)-[6]-Dehydroparadol|cas:878006-06-5|西域试剂

(E)-[6]-Dehydroparadol,95.0%

产品编号：Bellancom-77293| CAS NO：878006-06-5| 分子式：C₁₇H₂₄O₃| 分子量：276.37

本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用，

货号	价格	库存与货期
Bellancom-77293	￥900.00	杭州北京（现货）
Bellancom-77293	￥1500.00	杭州北京（现货）
Bellancom-77293	￥3800.00	杭州北京（现货）
Bellancom-77293	￥4800.00	杭州北京（现货）
Bellancom-77293	￥9800.00	杭州北京（现货）

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(E)-[6]-Dehydroparadol

产品介绍

(E)-[6]-Dehydroparadol 是 [6]-Shogaol (HY-14616) 的氧化代谢产物，是一种有效的 Nrf2 活化剂。(E)-[6]-Dehydroparadol 可抑制人癌细胞的生长并诱导其凋亡。

生物活性

(E)-[6]-Dehydroparadol, an oxidative metabolite of [6]-Shogaol (HY-14616), is a potent Nrf2 activator. (E)-[6]-Dehydroparadol can inhibit the growth and induce the apoptosis of human cancer cells.

体外研究

(E)-[6]-Dehydroparadol (M15) (5-80 µM; 24 h) inhibits the growth of HCT-116 and H-1299 cells, with IC₅₀s of 43.02 and 41.59 µM, respectively.
(E)-[6]-Dehydroparadol (10-40 µM; 24 h) induces apoptosis in HCT-116 and H-1299 cells.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

(E)-[6]-Dehydroparadol (compound 19) (5 µM; 24 h) enhances Tg[glutathione S-transferase pi 1 (gstp1):green fluorescent protein (GFP)] fluorescence signal in the Tg(gstp1:GFP) transgenic zebrafish embryos.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

性状

Solid

溶解性数据

In Vitro:

DMSO : ≥ 140 mg/mL (506.57 mM)

* "≥" means soluble, but saturation unknown.

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	3.6183 mL	18.0917 mL	36.1834 mL
5 mM	0.7237 mL	3.6183 mL	7.2367 mL
10 mM	0.3618 mL	1.8092 mL	3.6183 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式