N-Boc-PEG5-bromide|cas:1392499-32-9|西域试剂

N-Boc-PEG5-bromide

产品编号：Bellancom-120702| CAS NO：1392499-32-9| 分子式：C₁₅H₃₀BrNO₆| 分子量：400.31

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货号	价格	库存与货期
Bellancom-120702	￥210.00	杭州北京（现货）
Bellancom-120702	￥350.00	杭州北京（现货）
Bellancom-120702	￥700.00	杭州北京（现货）

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N-Boc-PEG5-bromide

产品介绍

N-Boc-PEG5-bromide 是一种 PROTAC 连接桥，属于 PEG 类和 Alkyl/ether 类。N-Boc-PEG5-bromide 可用于合成一系列 PROTAC 分子。N-Boc-PEG5-bromide 是一种可降解 (cleavable) 的 ADC 连接桥，用于抗体活性分子结合物 (ADCs) 的合成。

生物活性

N-Boc-PEG5-bromide is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. N-Boc-PEG5-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

体外研究

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

性状

Liquid

溶解性数据

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式