m-PEG12-OH|cas:2050595-03-2|西域试剂

m-PEG12-OH

产品编号：Bellancom-141220| CAS NO：2050595-03-2| 分子式：C₂₅H₅₂O₁₃| 分子量：560.67

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货号	价格	库存与货期
Bellancom-141220	￥210.00	杭州北京（现货）
Bellancom-141220	￥350.00	杭州北京（现货）
Bellancom-141220	￥490.00	杭州北京（现货）

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m-PEG12-OH

产品介绍

m-PEG12-OH 是一种 PROTAC linker，属于 PEG 类，可用于合成 PROTAC 分子。m-PEG12-OH 也是一种不可降解 (non-cleavable) 的含 12 个单元 PEG 的 ADC linker，可用于合成抗体偶联活性分子 (ADC)。

生物活性

m-PEG12-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. m-PEG12-OH is also a non-cleavable 12 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

体外研究

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

性状

Liquid

溶解性数据

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式