Propargyl-PEG3-acid|cas:1347760-82-0|西域试剂

Propargyl-PEG3-acid,98.0%

产品编号：Bellancom-126975| CAS NO：1347760-82-0| 分子式：C₁₀H₁₆O₅| 分子量：216.23

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货号	包装	价格	库存与货期	购买量	操作
Bellancom-126975		￥400.00	杭州北京（现货）
Bellancom-126975		￥640.00	杭州北京（现货）

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Propargyl-PEG3-acid

产品介绍

Propargyl-PEG3-acid是一种不可降解 (non-cleavable) 的含 3 个单元 PEG 的 ADC linker，同时也是基于PEG的PROTAC linker,可用于合成6-OHDA-PEG3-yne。6-OHDA-PEG3-yne 包含6-OHDA (HY-B1081, HY-B1081A) 和Propargyl-PEG3-acid。

生物活性

Propargyl-PEG3-acid is a non-cleavable (3 unit PEG) ADC linker and also a PEG-based PROTAC linker that can be used to synthesis 6-OHDA-PEG3-yne. 6-OHDA-PEG3-yne contains 6-OHDA (HY-B1081, HY-B1081A) and Propargyl-PEG3-acid.

体外研究

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

性状

Liquid

溶解性数据

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式