(S,R,S)-AHPC-Me-C10-NH2
产品编号:Bellancom-130847| CAS NO:2376139-52-3| 分子式:C34H53N5O4S| 分子量:627.88
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(S,R,S)-AHPC-Me-C10-NH2
产品介绍 | (S,R,S)-AHPC-Me-C5-COOH 是一种合成的 E3 连接酶配体结合物,它结合了 VHL 配体和 linker。(S,R,S)-AHPC-Me-C5-COOH 可用于 PROTAC MS432 (HY-130602)。 |
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生物活性 | (S,R,S)-AHPC-Me-C10-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the a VHL ligand and a linker. (S,R,S)-AHPC-Me-C10-NH2 can be used in PROTAC MS432 (HY-130602). |
体外研究 |
MS432 is a first-in-class and highly selective PD0325901-based VHL-recruiting PROTAC degrader for MEK1 and MEK2. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. |
体内研究 | |
体内研究 | |
性状 | Solid |
溶解性数据 | |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 |
-20°C, protect from light, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen) |
参考文献 |