SCD1 inhibitor-3|cas:1282606-48-7|西域试剂

SCD1 inhibitor-3,98.55%

产品编号：Bellancom-139077| CAS NO：1282606-48-7| 分子式：C₁₉H₁₆FN₇O₂| 分子量：393.37

本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用，

货号	价格	库存与货期
Bellancom-139077	￥2500.00	杭州北京（现货）
Bellancom-139077	￥3800.00	杭州北京（现货）
Bellancom-139077	￥7500.00	杭州北京（现货）
Bellancom-139077	￥12000.00	杭州北京（现货）

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SCD1 inhibitor-3

产品介绍

SCD1 inhibitor-3是一种安全、有效的具有口服活性的 SCD1 抑制剂。SCD1 inhibitor-3 可用于肥胖症、二型糖尿病、血脂异常等代谢性疾病，以及皮肤病、痤疮、癌症等的研究。

生物活性

SCD1 inhibitor-3 is a safe, potent and orally active SCD1 inhibitor. SCD1 inhibitor-3 can be used for the research of metabolic diseases such as obesity, type II diabetes and dyslipidemia, as well as skin diseases, acne and cancer.

体外研究

体内研究

SCD1 inhibitor-3 (compound 17a) (5 mg/kg; p.o.; 4 hours) reduces the plasma C16:1/C16:0 triglycerides desaturation index by 54 %.
SCD1 inhibitor-3 (2~10 mg/kg; p.o.; 4 hours) makes a dose-responsive reduction of plasma triglycerides desaturation index.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Lewis rats
Dosage:	5 mg/kg
Administration:	P.o.; 4 hours
Result:	Reduced the plasma C16:1/C16:0 triglycerides desaturation index by 54 %.

Animal Model:	Lewis rats
Dosage:	2~10 mg/kg
Administration:	P.o.; 4 hours
Result:	A dose-responsive reduction of plasma triglycerides desaturation index.

体内研究

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Lewis rats
Dosage:	5 mg/kg
Administration:	P.o.; 4 hours
Result:	Reduced the plasma C16:1/C16:0 triglycerides desaturation index by 54 %.

Animal Model:	Lewis rats
Dosage:	2~10 mg/kg
Administration:	P.o.; 4 hours
Result:	A dose-responsive reduction of plasma triglycerides desaturation index.

性状

Solid

溶解性数据

In Vitro:

DMSO : ≥ 125 mg/mL (317.77 mM)

* "≥" means soluble, but saturation unknown.

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	2.5421 mL	12.7107 mL	25.4214 mL
5 mM	0.5084 mL	2.5421 mL	5.0843 mL
10 mM	0.2542 mL	1.2711 mL	2.5421 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式