m-PEG2-O-Ph-NH2

产品编号:Bellancom-W096113| CAS NO:65673-48-5| 分子式:C11H17NO3| 分子量:211.26

m-PEG2-O-Ph-NH2 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。

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货号 包装 价格 库存与货期 购买量 操作
Bellancom-W096113
450.00 杭州 北京(现货)
Bellancom-W096113
720.00 杭州 北京(现货)
Bellancom-W096113
990.00 杭州 北京(现货)

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m-PEG2-O-Ph-NH2

产品介绍 m-PEG2-O-Ph-NH2 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。
生物活性

m-PEG2-O-Ph-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

体外研究

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
体内研究
性状Liquid
溶解性数据
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

参考文献

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文献:Stein, Marco; Trauner, Dirk; Middendorp, Simon J.; Carta, Valentina; Sigel, Erwin; Pejo, Ervin; Raines, Douglas E.; Forman, Stuart A. Angewandte Chemie, International Edition, 2012 , vol. 51, # 42 p. 10500 - 10504,5 Angewandte Chemie, 2012 , vol. 124, # 42 p. 10652 - 10656,5 Title/Abstract Full Text Show Details Stein, Marco; Middendorp, Simon J.; Carta, Valentina; Pejo, Ervin; Raines, Douglas E.; Forman, Stuart A.; Sigel, Erwin; Trauner, Dirk Angewandte Chemie - International Edition, 2012 , vol. 51, # 42 p. 10500 - 10504 Angew. Chem., 2012 , vol. 124, # 42 p. 10652 - 10656,5

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文献:Stein, Marco; Trauner, Dirk; Middendorp, Simon J.; Carta, Valentina; Sigel, Erwin; Pejo, Ervin; Raines, Douglas E.; Forman, Stuart A. Angewandte Chemie, International Edition, 2012 , vol. 51, # 42 p. 10500 - 10504,5 Angewandte Chemie, 2012 , vol. 124, # 42 p. 10652 - 10656,5 Title/Abstract Full Text Show Details Stein, Marco; Middendorp, Simon J.; Carta, Valentina; Pejo, Ervin; Raines, Douglas E.; Forman, Stuart A.; Sigel, Erwin; Trauner, Dirk Angewandte Chemie - International Edition, 2012 , vol. 51, # 42 p. 10500 - 10504 Angew. Chem., 2012 , vol. 124, # 42 p. 10652 - 10656,5
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