Bapotulimab BAY-1905254
产品编号:Bellancom-P99460| CAS NO:2359413-58-2
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Bapotulimab BAY-1905254
| 产品介绍 | Bapotulimab (BAY-1905254) 是一种全人 IgG2 抗体,靶向含有免疫球蛋白样结构域的受体 2 (ILDR2)。Bapotulimab 具有抗肿瘤和免疫抑制作用。 | ||||||||
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| 生物活性 | Bapotulimab (BAY-1905254) is a fully human IgG2 antibody targeting immunoglobulin-like domain containing receptor 2 (ILDR2). Bapotulimab has antitumor and immunosuppressive effects. | ||||||||
| 体外研究 |
Bapotulimab 阻断 ILDR2 对 T 细胞活化的免疫抑制作用。Bapotulimab 具有小鼠/人交叉反应性,因为 ILDR2 在人和鼠直系同源物的细胞外结构域之间具有 98% 的序列同一性。 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||
| 体内研究 |
Bapotulimab(BAY-1905254;10 mg/kg;腹腔注射;在第 1 天和第 4 天)显示抗原特异性 T 细胞增殖和细胞毒性显着增加。 西域 has not independently confirmed the accuracy of these methods. They are for reference only.
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| 体内研究 |
Bapotulimab(BAY-1905254;10 mg/kg;腹腔注射;在第 1 天和第 4 天)显示抗原特异性 T 细胞增殖和细胞毒性显着增加。 西域 has not independently confirmed the accuracy of these methods. They are for reference only.
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| 运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
| 储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. | ||||||||
| 参考文献 |

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