刺芒柄花素, 分析对照品|Formononetin|cas:485-72-3|西域试剂

刺芒柄花素, 分析对照品,Formononetin

产品编号：西域试剂-WR343558| CAS NO：485-72-3| MDL NO：MFCD00016948| 分子式：C₁₆H₁₂O₄| 分子量：268.26

Formononetin (Formononetol; Flavosil)提取自红三叶草，能剂量依赖的抑制DU-145/PC-3细胞增殖。

本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用，

货号	包装	价格	库存与货期	购买量	操作
西域试剂-WR343558		￥225.00	杭州北京（现货）

增值税发票√顺丰快递√订货电话：18601927057

产品名称

刺芒柄花素, 分析对照品

英文名称

Formononetin

CAS编号

485-72-3

产品描述

Formononetin (Formononetol; Flavosil)提取自红三叶草，能剂量依赖的抑制DU-145/PC-3细胞增殖。

产品熔点

256-260 °C

产品沸点

479.4±45.0 °C at 760 mmHg

产品密度

1.3±0.1 g/cm3

产品闪点

183.4±22.2 °C

精确质量

268.073547

PSA

59.67000

LogP

2.96

外观性状

无色针晶（丙酮）

蒸气压

0.0±1.2 mmHg at 25°C

折射率

1.641

溶解性

溶于甲醇、乙醇、丙酮

溶解性数据

In Vitro:

DMSO : ≥ 35 mg/mL (130.47 mM)

* "≥" means soluble, but saturation unknown.

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	3.7277 mL	18.6386 mL	37.2773 mL
5 mM	0.7455 mL	3.7277 mL	7.4555 mL
10 mM	0.3728 mL	1.8639 mL	3.7277 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用；以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

1.

请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% saline
Solubility: 2.5 mg/mL (9.32 mM); Suspended solution; Need ultrasonic

此方案可获得 2.5 mg/mL (9.32 mM) 的均匀悬浊液，悬浊液可用于口服和腹腔注射。
以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中，混合均匀；向上述体系中加入50 μL Tween-80，混合均匀；然后继续加入 450 μL生理盐水定容至 1 mL。
将 0.9 g 氯化钠，完全溶解于 100 mL ddH₂O 中，得到澄清透明的生理盐水溶液
2.

请依序添加每种溶剂： 10% DMSO 90% (20% SBE-β-CD in saline)
Solubility: 2.5 mg/mL (9.32 mM); Suspended solution; Need ultrasonic

此方案可获得 2.5 mg/mL (9.32 mM) 的均匀悬浊液，悬浊液可用于口服和腹腔注射。
以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中，混合均匀。
将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中，再用生理盐水定容至 10 mL，完全溶解，澄清透明
3.

请依序添加每种溶剂： 10% DMSO 90% corn oil
Solubility: ≥ 2.5 mg/mL (9.32 mM); Clear solution

此方案可获得 ≥ 2.5 mg/mL (9.32 mM，饱和度未知) 的澄清溶液，此方案不适用于实验周期在半个月以上的实验。
以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中，混合均匀。

*以上所有助溶剂都可在西域网站选购。

体外研究

Formononetin 是从 Astragalus membranaceus 中分离出来的主要异黄酮成分之一，已被证明具有多种药理益处。Formononetin 在人结肠癌细胞中具有抗血管生成活性。Formononetin 还通过下调人前列腺癌细胞中的 Akt/细胞周期蛋白 D1/CDK4 促进细胞周期停滞。
Formononetin (25-150 μM) 显著降低 FGF2 刺激的内皮细胞增殖。

XIYU has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay

Cell Line:	HUVECs
Concentration:	0, 10, 25, 50, 75, 100, and 150 μM
Incubation Time:
Result:	Significantly decreased the proliferation of HUVECs stimulated by FGF2 in a dose-dependent manner, while had little inhibitory effects on HUVECs that were not stimulated by FGF2.

体内研究

Formononetin 显著抑制肿瘤体积，并且与载体组相比，Formononetin 处理组的肿瘤重量得到显著抑制。Formononetin 处理耐受性良好，赋形剂组与 Formononetin 处理组体重无显著差异。

XIYU has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	BALB/c nude mice bearing MDA-MB-231 xenografts
Dosage:	100 mg/kg
Administration:	Treated daily by intragastric administration for 25 days
Result:	Inhibited breast cancer growth and angiogenesis in vivo.

动物实验

*下述溶液配置方法仅为基于分子量计算出的理论值。不同产品在配置溶液前，需考虑其在不同溶剂中的溶解度限制。

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.7276 mL	18.6379 mL	37.2759 mL
5 mM	0.7455 mL	3.7276 mL	7.4552 mL
10 mM	0.3728 mL	1.8638 mL	3.7276 mL

不同实验动物依据体表面积的等效剂量转换表（参考来源于公开文献）

	小鼠	大鼠	兔	豚鼠	仓鼠	狗
重量 (kg)	0.02	0.15	1.8	0.4	0.08	10
体表面积 (m²)	0.007	0.025	0.15	0.05	0.02	0.5
K_m 系数	3	6	12	8	5	20

动物 A (mg/kg) = 动物 B (mg/kg) ×	动物 B的K_m系数
	动物 A的K_m系数

例如，依据体表面积折算法，将化合物用于小鼠的剂量20 mg/kg 换算成大鼠的剂量，需要将20 mg/kg 乘以小鼠的K_m系数（3），再除以大鼠的K_m系数（6），得到化合物用于大鼠的等效剂量为10 mg/kg。

稳定性

按规格使用和贮存，不会发生分解，避免与氧化物接触

储存条件

储存条件: 2-8°C

运输方式: 冰袋运输，根据产品的不同，可能会有相应调整。

化学品安全说明书(MSDS)

下载MSDS

质检证书(COA)

符号	GHS07
信号词	Warning
危害声明	H315-H319-H335
警示性声明	P280-P305 + P351 + P338-P337 + P313
个人防护装备	dust mask type N95 (US);Eyeshields;Gloves
危害码 (欧洲)	Xi:Irritant
风险声明 (欧洲)	R36/37/38
安全声明 (欧洲)	S37/39-S26-S36
危险品运输编码	NONH for all modes of transport
海关编码	2932999099

1. 物质的识别

产品名：	Formononetin
CAS号：	485-72-3
制造商/供应商：	西域试剂网站：www.hzbp.cn 邮件：13911702513@139.com

2. 合成/成分数据

产品名：	Formononetin
别名：	Biochanin B; Flavosil; Formononetol
分子式：	C16H12O4
分子量：	268.27

3. 急救措施

吸入后：	如果吸入，移至空气新鲜处，如果呼吸困难，给输氧，如呼吸停止，给予人工呼吸。
皮肤接触后：	用大量的水冲洗，移除污染的衣服和鞋子。
眼睛接触后：	检查并取下隐形眼镜，并用大量的水冲洗；呼叫医生。
吞食后：	如果吞食，用大量纯净水漱口；呼叫医生。

4. 消防措施

适当的灭火剂：	雾状水，二氧化碳，干粉或泡沫。
防护设备：	穿戴自给式呼吸器和防护服，以防止与皮肤和眼睛接触。

5. 泄漏应急处理

安全防范措施：	封锁泄漏区域；穿戴自给式呼吸器，防护服和厚橡胶手套。
清洁/收集措施：	使用液体粘合原料（硅藻土，通用粘合剂）吸取精细粉末；使用酒精擦洗表面和设备除去污渍；根据第11条处理被污染的材料。

6. 处理和储存

安全处理说明：	避免吸入和接触皮肤，眼睛及衣物；材料可能略微具有刺激性。
储存：	粉末型式 -20°C 3年；4°C 2年溶于溶剂 -80°C 6个月；-20°C 1个月

7. 接触控制和个人防护

呼吸设备：	NIOSH / MSHA认可的呼吸器。
双手保护：	耐化学腐蚀的橡胶手套。
眼睛防护：	化学安全护目镜。

8. 稳定性和反应活性

稳定性：	按照说明存储是稳定的；避免强氧化剂。
热分解/其他要避免的情况：	避免光和热。

9. 毒性资料

急性毒性：	无可用资料。
主要刺激性影响：	无可用资料。
在皮肤上：	无可用资料。
对眼睛：	无可用资料；可能具有刺激性。

10. 生态资料

一般注意事项：

无可用资料。

11. 废弃处置

按照所在国家，省份，县市和地方的法规处置。

12. 运输信息

正确的运输名称：	无
非危险品运输：	这种物质被视为非危险品运输。

13. 法规信息

尚未有针对此产品作出的化学安全性评估。

14. 其他信息

上游产品 5
2632-13-5 95-01-2 487-49-0 68-12-2
486-66-8
下游产品 10
10499-17-9 486-62-4 897-46-1 37816-19-6
20575-57-9 486-66-8 531-95-3 1157-39-7
32383-76-9 949021-68-5

65. [3.614] Shu-Yun Yang et al."An integrated approach of HPLC-MS-based chemical profiling, network pharmacology, and molecular docking to reveal the potential mechanisms of Qishen Gubiao Granules for treating COVID-19."JOURNAL OF SEPARATION SCIENCE.2023 Mar;:2200953

64. [4.927] Chenghui Pan et al."The Fate and Intermediary Metabolism of Soyasapogenol in the Rat."MOLECULES.2023 Jan;28(1):284

63. [6.449] Yanmei Li et al."Regional variations and plant compartments shape the community structures of the endophytic microbiome and secondary metabolites of Astragalus mongholicus."INDUSTRIAL CROPS AND PRODUCTS.2023 Feb;192:116037

62. [6.656] Ying Yang et al."Formononetin improves cardiac function and depressive behaviours in myocardial infarction with depression by targeting GSK-3β to regulate macrophage/microglial polarization."PHYTOMEDICINE.2022 Dec;:154602

61. [6.656] Chong Chen et al."Yishen-Qingli-Huoxue Formula attenuates renal fibrosis by inhibiting indoxyl sulfate via AhR/snai1 signaling."PHYTOMEDICINE.2022 Nov;:154546

60. [IF=1.698] Jinyan Wu et al."Chemical Identification and Antioxidant Screening of Bufei Yishen Formula using an Offline DPPH Ultrahigh-Performance Liquid Chromatography Q-Extractive Orbitrap MS/MS."International Journal of Analytical Chemistry.2022 Oct 15;2022:142380

59. [IF=3.571] Yuhao Zhang et al."A novel strategy integrating gas phase fractionation with staggered mass range and LC-MS/MS molecular network for comprehensive metabolites profiling of Gui Ling Ji in rats."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS.2023 Jan;222

58. [IF=5.988] Jun Li et al."Screening of anti-heart failure active compounds from fangjihuangqi decoction in verapamil-induced zebrafish model by anti-heart failure index approach.."Frontiers in Pharmacology.2022 Oct;13:999950-999950

57. [IF=5.168] Pan Wang et al."Discovery and characterization of novel ATP citrate lyase inhibitors from natural products by a luminescence-based assay."CHEMICO-BIOLOGICAL INTERACTIONS.2022 Nov;367:110199

56. [IF=6.208] Pan Wang et al."Discovery of Flavonoids as Novel Inhibitors of ATP Citrate Lyase: Structure–Activity Relationship and Inhibition Profiles."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2022 Jan;23(18):10747

55. [IF=9.231] Tong Zhao et al."Identification of characteristic markers for monofloral honey of Astragalus membranaceus var. mongholicus Hsiao: A combined untargeted and targeted MS-based study."FOOD CHEMISTRY.2022 Sep;:134312

54. [IF=1.978] Chen Ming-jun et al."Composite Sophora Colon-Soluble Capsule Ameliorates DSS-Induced Ulcerative Colitis in Mice via Gut Microbiota-Derived Butyric Acid and NCR+ ILC3."Chin J Integr Med. 2022 Apr;:1-10

53. [IF=6.576] Junkun Pan et al."Inhibition of Dipeptidyl Peptidase-4 by Flavonoids: Structure–Activity Relationship, Kinetics and Interaction Mechanism."Frontiers in Nutrition. 2022; 9: 892426

52. [IF=5.34] Lei Jin et al."Simultaneous optimization of the extraction process of Yangyin Yiqi Huoxue prescription with natural deep eutectic solvents for optimal extraction yield and antioxidant activity: A comparative study of two models."PHYTOMEDICINE. 2022 Jul;102

51. [IF=3.645] Jingbin Chen et al.Screening for potential quality markers of Callerya nitida var. hirsutissima. Z.Wei based on components profile, pharmacokinetics, and anti-inflammatory study.Journal Of Separation Science.2021 Nov 02

50. [IF=2.629] Li Tingting et al."Quality Assessment of Licorice Based on Quantitative Analysis of Multicomponents by Single Marker Combined with HPLC Fingerprint."Evid-Based Compl Alt. 2021;2021:8834826

49. [IF=2.629] Wang Lingdi et al."Danggui Buxue Tang Rescues Folliculogenesis and Ovarian Cell Apoptosis in Rats with Premature Ovarian Insufficiency."Evid-Based Compl Alt. 2021;2021:6614302

48. [IF=2.633] Ruoke Ma et al."Variation of Chemical Components in Sapwood, Transition Zone, and Heartwood of Dalbergia odorifera and Its Relationship with Heartwood Formation."Forests. 2021 May;12(5):577

47. [IF=2.984] Chenkai Wang et al."Comparative transcriptome analysis of roots, stems, and leaves of Pueraria lobata (Willd.) Ohwi: identification of genes involved in isoflavonoid biosynthesis."Peerj. 2021 Feb;9:e10885

46. [IF=3] Qu Lala et al."Phenotypic assessment and ligand screening of ETA/ETB receptors with label-free dynamic mass redistribution assay."N-S Arch Pharmacol. 2020 Jun;393(6):937-950

45. [IF=3.361] Yuhao Zhang et al."An integrated approach for structural characterization of Gui Ling Ji by traveling wave ion mobility mass spectrometry and molecular network."Rsc Adv. 2021 Apr;11(26):15546-15556

44. [IF=3.69] Qian Zhang et al."Qishen Granule alleviates endoplasmic reticulum stress-induced myocardial apoptosis through IRE-1-CRYAB pathway in myocardial ischemia."J Ethnopharmacol. 2020 Apr;252:112573

43. [IF=4.142] Hu Guizhou et al."An integrated strategy for the identification and screening of anti-allergy components from natural products based on calcium fluctuations and cell extraction coupled with HPLC–Q–TOF–MS."Anal Bioanal Chem. 2021 Oct;413(25):6253-6266

42. [IF=4.225] Zhang Wei et al."Five Active Components Compatibility of Astragali Radix and Angelicae Sinensis Radix Protect Hematopoietic Function Against Cyclophosphamide-Induced Injury in Mice and t-BHP–Induced Injury in HSCs."Front Pharmacol. 2019 Aug;0:936

41. [IF=4.411] Liyu Luo et al."Integrated Phytochemical Analysis Based on UPLC-MS and Network Pharmacology Approaches to Explore the Quality Control Markers for the Quality Assessment of Trifolium pratense L.."Molecules. 2020 Jan;25(17):3787

40. [IF=4.411] Mengyang Hou et al."Preparative Purification of Total Flavonoids from Sophora tonkinensis Gagnep. by Macroporous Resin Column Chromatography and Comparative Analysis of Flavonoid Profiles by HPLC-PAD."Molecules. 2019 Jan;24(17):3200

39. [IF=4.486] Xin Li et al."Formononetin, J1 and J2 have different effects on endothelial cells via EWSAT1‐TRAF6 and its downstream pathway."J Cell Mol Med. 2020 Jan;24(1):875-885

38. [IF=4.759] Wenjie Wu et al."An analytical strategy for accurate, rapid and sensitive quantitative analysis of isoflavones in traditional Chinese medicines using ultra-high performance supercritical fluid chromatography: Take Radix Puerariae as an example."J Chromato

37. [IF=4.769] Zhenzhong Yang et al."Deciphering bioactive compounds of complex natural products by tandem mass spectral molecular networking combined with an aggregation-induced emission based probe."J Pharm Anal. 2020 Nov;:

36. [IF=4.879] Yang Liu et al."UV-B Radiation Largely Promoted the Transformation of Primary Metabolites to Phenols in Astragalus mongholicus Seedlings."Biomolecules. 2020 Apr;10(4):504

35. [IF=5.81] Gu Junfei et al."Standardized Astragalus Mongholicus Bunge-Curcuma Aromatica Salisb. Extract Efficiently Suppresses Colon Cancer Progression Through Gut Microbiota Modification in CT26-Bearing Mice."Front Pharmacol. 2021 Aug;0:2278

34. [IF=8.579] Chuanrui Ma et al."Formononetin attenuates atherosclerosis via regulating interaction between KLF4 and SRA in apoE-/- mice."Theranostics. 2020; 10(3): 1090–1106

33. [IF=2.705] Shu Yang et al."Formononetin ameliorates cholestasis by regulating hepatic SIRT1 and PPARα."Biochem Bioph Res Co. 2019 May;512:770

32. [IF=3.208] Teng Li et al."Formononetin induces vasorelaxation in rat thoracic aorta via regulation of the PI3K/PTEN/Akt signaling pathway."Drug Des Dev Ther. 2018; 12: 3675–3684

31. [IF=3.361] Taofang Cheng et al."Hybrid multidimensional data acquisition and data processing strategy for comprehensive characterization of known, unknown and isomeric compounds from the compound Dan Zhi Tablet by UPLC-TWIMS-QTOFMS."Rsc Adv. 2019 Mar;9(16):8714-8727

30. [IF=3.738] Selma Houchi et al."Investigation of common chemical components and inhibitory effect on GES-type β-lactamase (GES22) in methanolic extracts of Algerian seaweeds."Microb Pathogenesis. 2019 Jan;126:56

29. [IF=3.935] Ziying Liu et al."Promotion of classic neutral bile acids synthesis pathway is responsible for cholesterol-lowing effect of Si-miao-yong-an decoction: Application of LC–MS/MS method to determine 6 major bile acids in rat liver and plasma."J Pharmaceut Bio

28. [IF=3.935] Nan Mi et al."Metabolite profiling of traditional Chinese medicine formula Dan Zhi Tablet: An integrated strategy based on UPLC-QTOF/MS combined with multivariate statistical analysis."J Pharmaceut Biomed. 2019 Feb;164:70

27. [IF=4.411] Liangliang Liu et al."Rapid Screening and Identification of BSA Bound Ligands from Radix astragali Using BSA Immobilized Magnetic Nanoparticles Coupled with HPLC-MS."Molecules. 2016 Nov;21(11):1471

26. [IF=4.411] Jing Zhou et al."Simultaneous Optimization for Ultrasound-Assisted Extraction and Antioxidant Activity of Flavonoids from Sophora flavescens Using Response Surface Methodology."Molecules. 2019 Jan;24(1):112

25. [IF=4.522] Wei Hu et al."In vitro and in vivo studies of antiosteosarcoma activities of formononetin."J Cell Physiol. 2019 Oct;234(10):17305-17313

24. [IF=4.759] Yuping Zhang et al."On-line surface plasmon resonance-high performance liquid chromatography–tandem mass spectrometry for analysis of human serum albumin binders from Radix Astragali."J Chromatogr A. 2013 Jun;1293:92

23. Yang, Zhenzhong, et al. "Deciphering bioactive compounds of complex natural products by tandem mass spectral molecular networking combined with an aggregation-induced emission based probe." Journal of Pharmaceutical Analysis (2020).https://doi.org/10.1016/

22. Mi, Nan, et al. "Metabolite profiling of traditional Chinese medicine formula Dan Zhi Tablet: an integrated strategy based on UPLC-QTOF/MS combined with multivariate statistical analysis." Journal of pharmaceutical and biomedical analysis 164 (2019): 70-85

21. Wang, Lingdi, et al. "Danggui Buxue Tang Rescues Folliculogenesis and Ovarian Cell Apoptosis in Rats with Premature Ovarian Insufficiency." Evidence-Based Complementary and Alternative Medicine 2021 (2021).https://doi.org/10.1155/2021/6614302

20. Wang, Qian, et al. "Identification and pharmacokinetics of multiple constituents in rat plasma after oral administration of Yinchenzhufu decoction." Journal of ethnopharmacology 153.3 (2014): 714-724.https://doi.org/10.1016/j.jep.2014.03.039

19. Peng-Peng, L. I. U., et al. "Metabolomics analysis and rapid identification of changes in chemical ingredients in crude and processed Astragali Radix by UPLC-QTOF-MS combined with novel informatics UNIFI platform." Chinese journal of natural medicines 16.9

18. 毛文点,庹玲玲,齐文续,苏睿智,邓常清,邹龙.黄芪-当归不同配伍对其6种主要有效成分溶出的影响[J].湖南中医药大学学报,2021,41(03):350-354.

17. 冯紫薇. 子洲黄芪饮片质量等级标准研究[D].北京中医药大学,2020.

16. 田文仓. 不同生长年限及采收期子洲黄芪鉴别特征及其质量、产量差异分析[D].北京中医药大学,2020.

15. 徐艳阳,赵玉娟,高峰,王二雷,鲁海玲,李雪凤,姜雯雯,陈艳.高效液相色谱法分析中国人参不同部位中多酚类化合物[J].食品科学,2021,42(04):240-246.

14. 常冠华,薄颖异,崔洁,徐露露,赵梓邯,王文全,侯俊玲.基于UPLC-Q-Exactive Orbitrap-MS分析甘草地上部分主要化学成分[J].中国中药杂志,2021,46(06):1449-1459.

13. 孙秀蕊,魏桂杰,王宏雅,赵雯雯,张哲,张婷,魏锋,张玉杰.基于外观性状和内在成分的黄芪药材质量等级评价[J].中国中药杂志,2021,46(04):966-971.

12. 杨雨桐,张卿硕,符韵林,孙静.巴里黄檀心材色素成分及其稳定性和抗氧化性[J].林业科学,2021,57(03):126-134.

11. 勾玲,唐珍,苏春蓝,姚水莲,卢海啸.牛大力标准提取物制备工艺研究[J].海峡药学,2020,32(11):1-3.

10. 余颖, 樊金玲, 程源斌,等. 甘草酸提取废液α-葡萄糖苷酶抑制剂的筛选与鉴定[J]. 食品科学, 2018, 39(13).

9. 李欣, 卓冰雨, 祁晓娟,等. 黄芪异黄酮含量与气候因子的灰色关联度和通径分析[J]. 中国中药杂志 2020年45卷14期, 3407-3413页, MEDLINE ISTIC PKU CSCD CA BP, 2020.

8. 侯美如, 尹珺伊, 王岩,等. 黄芪发酵前后黄酮含量及指纹图谱比较研究[J]. 中国兽药杂志, 2018, v.52(05):52-58.

7. 刘杰何钢刘贤桂等. 人工栽培鸡血藤中五种黄酮类物质含量测定[J]. 分子植物育种 2017 015(009):3832-3837.

6. 尚兴朴,欧阳罗丹,肖苏萍,王继永,高永坚,袁春平,刘畅.黄芪饮片质量评价和分级标准探讨[J].中国现代中药,2020,22(05):772-779.

5. 黎映琼蔡庆群苏志强等. 不同产地黄芪根茎叶中4种异黄酮类成分的比较及其聚类分析[J]. 现代中药研究与实践 2020 v.34;No.173(02):69-73.

4. 刘雪石晓倩吴晏杰等. UPLC法同时测定新安名方脑络欣通中5个活性成分的含量[J]. 贵阳中医学院学报 2020年42卷4期 26-31页 ISTIC 2020.

3. 勾玲, 唐珍, 苏春蓝,等. 牛大力黄酮类成分提取条件的优化[J]. 检验检疫学刊, 2020, 030(002):P.78-80.

2. 刘洋, 张鑫, 石秀佳,等. 基于PBPK模型的在体单向肠灌流技术对苷元成分的适用性分析评价[J]. 中国中药杂志, 2019(17):3645-3652.

1. 陆晖陆瑞勇.HPLC测定玉郎伞中芒柄花素的含量[J].中国民族民间医药 2013 22(18):25-26.