Peptide YY Fragment 3-36 human|cas:126339-09-1|西域试剂

Peptide YY Fragment 3-36 human,≥98% (HPLC),冻干粉

产品编号：西域试剂-WR358530| CAS NO：126339-09-1| MDL NO：MFCD00165623| 分子式：C₁₈₀H₂₇₉N₅₃O₅₄| 分子量：4049.55

Peptide YY (PYY) (3-36), porcine 是一种肠胃激素肽，作为 Y2 受体的激动剂，能够降低食欲。

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货号	包装	价格	库存与货期	购买量	操作
西域试剂-WR358530		￥1800.00	杭州北京（现货）
西域试剂-WR358530		￥3500.00	杭州北京（现货）

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产品名称

Peptide YY Fragment 3-36 human

CAS编号

126339-09-1

产品描述

Peptide YY (PYY) (3-36), porcine 是一种肠胃激素肽，作为 Y2 受体的激动剂，能够降低食欲。

溶解性

Water

溶解性数据

In Vitro:

H₂O

Peptide Solubility and Storage Guidelines:

1. Calculate the length of the peptide.

2. Calculate the overall charge of the entire peptide according to the following table:

	Contents	Assign value
Acidic amino acid	Asp (D), Glu (E), and the C-terminal -COOH.	-1
Basic amino acid	Arg (R), Lys (K), His (H), and the N-terminal -NH₂	+1
Neutral amino acid	Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q)	0

3. Recommended solution:

Overall charge of peptide	Details
Negative (<0)	1. Try to dissolve the peptide in water first. 2. If water fails, add NH₄OH (<50 μL). 3. If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0)	1. Try to dissolve the peptide in water first. 2. If water fails, try dissolving the peptide in a 10%-30% acetic acid solution. 3. If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0)	1. Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first. 2. For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

体外研究

Peptide YY (PYY) (3-36), porcine is a Y2 receptor agonist, generated via cleaving the first two amino acids at the N terminus of PYY1-36 by enzyme dipeptidyl peptidase-IV (DPP-IV), and can reduces food intake.

体内研究

In mice, actinonin significantly prolongs the anorectic effect of PYY_3-36 (50 nmol/kg) and maintains higher PYY_3-36 plasma levels than treatment with PYY_3-36 alone.

动物实验