木瓜蛋白酶, ≥3 units/mg|Papain|cas:9001-73-4|西域试剂

木瓜蛋白酶, ≥3 units/mg,Papain

产品编号：西域试剂-WR360024| CAS NO：9001-73-4| MDL NO：MFCD00131791| 分子式：C₁₉H₂₉N₇O₆| 分子量：451.477

Papain 是肽酶 C1 家族中的一种半胱氨酸蛋白酶，广泛应用于食品、医药、纺织、化妆品等。Papain是一种蛋白水解酶，组织蛋白酶Cathepsin是木瓜蛋白酶家族中的一种半胱氨酸蛋白酶。此外，Papain可用于构建兔膝关节炎模型。

本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用，

货号	价格	库存与货期
西域试剂-WR360024	￥70.00	杭州北京（现货）
西域试剂-WR360024	￥166.00	杭州北京（现货）
西域试剂-WR360024	￥478.00	杭州北京（现货）
西域试剂-WR360024	￥1518.00	杭州北京（现货）

增值税发票√顺丰快递√订货电话：18601927057

产品名称

木瓜蛋白酶, ≥3 units/mg

英文名称

Papain

CAS编号

9001-73-4

产品描述

产品密度

1.5±0.1 g/cm3

产品闪点

29 °C

精确质量

451.217926

LogP

-1.47

外观性状

白色至米黄色粉末

折射率

1.652

溶解性

H2O: soluble1.2mg/mL | Soluble in water, insoluble in most organic solvents.

溶解性数据

In Vitro:

H₂O : 50 mg/mL (Need ultrasonic)

DMSO : 5 mg/mL (Need ultrasonic)

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用；以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

1.

请依序添加每种溶剂： PBS
Solubility: 50 mg/mL (Infinity mM); Clear solution; Need ultrasonic

*以上所有助溶剂都可在西域网站选购。

体外研究

木瓜蛋白酶是肽酶C1家族的半胱氨酸蛋白酶，其用于食品，药物，纺织品和化妆品工业。

细胞实验

酶活定义： 1g 固体酶（或 1mL 液体酶），在温度 37℃、pH7.0 条件下，1min 水解酪蛋白底物产生相当于 1µg 酪氨酸的酶量，为 1 个酶活力单位，以“U/g( 或 U/mL)”表示。

分子量：21000～23000

最适温度：37~60℃

最适pH：5.5~7.5

性状：为乳白色至微黄色粉末

成分：木瓜蛋白酶，葡萄糖

用途：一种能水解多肽、酰胺和酯的酶。其分子由212残基的折叠多肽键组成。微有吸湿性。对光敏感。不完全的溶于水和甘油，几乎不溶于多数有机溶剂。酶反应：裂解Arg-、Lys-、Phe-、X氨基酸。模型底物为苯甲酰精氨酸乙酯(BAEE)、N-苯甲酰-L-精氨酸对硝基苯胺(N-α-Bz-L-Arg-4-NA）、苄氧羰酰缬氨酰甘氨酰精氨酸对硝基苯胺(Chromozym TRY)。激活剂有半胱氨酸(Cys)、谷胱甘肽(GSH)、EDTA、还原剂、氰化物。抑制剂有汞(Hg2+)、其他重金属、碘乙酸、N-对基顺丁烯二

动物实验

*下述溶液配置方法仅为基于分子量计算出的理论值。不同产品在配置溶液前，需考虑其在不同溶剂中的溶解度限制。

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	4.4203 mL	22.1014 mL	44.2028 mL
5 mM	0.8841 mL	4.4203 mL	8.8406 mL
10 mM	0.442 mL	2.2101 mL	4.4203 mL

不同实验动物依据体表面积的等效剂量转换表（参考来源于公开文献）

	小鼠	大鼠	兔	豚鼠	仓鼠	狗
重量 (kg)	0.02	0.15	1.8	0.4	0.08	10
体表面积 (m²)	0.007	0.025	0.15	0.05	0.02	0.5
K_m 系数	3	6	12	8	5	20

动物 A (mg/kg) = 动物 B (mg/kg) ×	动物 B的K_m系数
	动物 A的K_m系数

例如，依据体表面积折算法，将化合物用于小鼠的剂量20 mg/kg 换算成大鼠的剂量，需要将20 mg/kg 乘以小鼠的K_m系数（3），再除以大鼠的K_m系数（6），得到化合物用于大鼠的等效剂量为10 mg/kg。

稳定性

1.常温常压下不稳定

2.避免湿，热，高温

3.对温度、PH和导致蛋白质变性的各种因素均非常敏感，极易受到外界条件的影响而改变其本身的构象和性质。

储存条件

储存条件: 2-8°C

运输方式: 冰袋运输，根据产品的不同，可能会有相应调整。

化学品安全说明书(MSDS)

下载MSDS

质检证书(COA)

符号	GHS07, GHS08
信号词	Danger
危害声明	H315-H319-H334-H335
警示性声明	P261-P305 + P351 + P338-P342 + P311
个人防护装备	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
危害码 (欧洲)	Xn
风险声明 (欧洲)	R42;R36/37/38
安全声明 (欧洲)	S22;S24;S26;S36/S37
危险品运输编码	NONH for all modes of transport
WGK德国	3
RTECS号	RU4950000

1. 物质的识别

产品名：	Papain
CAS号：	9001-73-4
制造商/供应商：	西域试剂网站：www.hzbp.cn 邮件：13911702513@139.com

2. 合成/成分数据

产品名：	Papain
别名：	arbuz; caroid; nematolyt
分子式：	C9H14N4O3
分子量：	226.23

3. 急救措施

吸入后：	如果吸入，移至空气新鲜处，如果呼吸困难，给输氧，如呼吸停止，给予人工呼吸。
皮肤接触后：	用大量的水冲洗，移除污染的衣服和鞋子。
眼睛接触后：	检查并取下隐形眼镜，并用大量的水冲洗；呼叫医生。
吞食后：	如果吞食，用大量纯净水漱口；呼叫医生。

4. 消防措施

适当的灭火剂：	雾状水，二氧化碳，干粉或泡沫。
防护设备：	穿戴自给式呼吸器和防护服，以防止与皮肤和眼睛接触。

5. 泄漏应急处理

安全防范措施：	封锁泄漏区域；穿戴自给式呼吸器，防护服和厚橡胶手套。
清洁/收集措施：	使用液体粘合原料（硅藻土，通用粘合剂）吸取精细粉末；使用酒精擦洗表面和设备除去污渍；根据第11条处理被污染的材料。

6. 处理和储存

安全处理说明：	避免吸入和接触皮肤，眼睛及衣物；材料可能略微具有刺激性。
储存：	2-8°C, dry, protect from light, sealed

7. 接触控制和个人防护

呼吸设备：	NIOSH / MSHA认可的呼吸器。
双手保护：	耐化学腐蚀的橡胶手套。
眼睛防护：	化学安全护目镜。

8. 稳定性和反应活性

稳定性：	按照说明存储是稳定的；避免强氧化剂。
热分解/其他要避免的情况：	避免光和热。

9. 毒性资料

急性毒性：	无可用资料。
主要刺激性影响：	无可用资料。
在皮肤上：	无可用资料。
对眼睛：	无可用资料；可能具有刺激性。

10. 生态资料

一般注意事项：

无可用资料。

11. 废弃处置

按照所在国家，省份，县市和地方的法规处置。

12. 运输信息

正确的运输名称：	无
非危险品运输：	这种物质被视为非危险品运输。

13. 法规信息

尚未有针对此产品作出的化学安全性评估。

14. 其他信息

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