环丙基[4-[3-(1H-咪唑-5-基)丙氧基]苯基]甲酮盐酸盐, ≥99% (HPLC), solid,Ciproxifan hydrochloride
产品编号：西域试剂-WR117869| CAS NO：1049741-81-2| MDL NO：MFCD08705321| 分子式：C16H18N2O2 · HCl| 分子量：306.79
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| 用途: | Ciproxifan belongs to a novel chemical series of histamine H3-receptor antagonists. In vitro, it behaved as a competitive antagonist at the H3 autoreceptor controlling 3H histamine release from synaptosomes and displayed similar Ki values (0.5-1.9 nM) at the H3 receptor controlling the electrically-induced contraction of guinea pig ileum or at the brain H3 receptor labeled with 125I-iodoproxyfan. Ciproxifan appears to be an orally bioavailable, extremely potent and selective H3-receptor antagonist whose vigilance- and attention-promoting effects are promising for therapeutic applications in aging disorders. |
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| 储存条件: | 2-8°C |
| 颜色: | 固体 |
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