2,4-二氯-5-碘嘧啶, 99%,2,4-Dichloro-5-iodopyrimidine
产品编号:西域试剂-WR374725| CAS NO:13544-44-0| MDL NO:MFCD01898087| 分子式:C4HCl2IN2| 分子量:274.87
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英文名称 | 2,4-Dichloro-5-iodopyrimidine |
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CAS编号 | 13544-44-0 |
产品熔点 | 70 °C |
产品沸点 | 310.2±22.0 °C at 760 mmHg |
产品密度 | 2.3±0.1 g/cm3 |
产品闪点 | 141.4±22.3 °C |
精确质量 | 273.856140 |
PSA | 25.78000 |
LogP | 2.67 |
外观性状 | 灰白色固体 |
蒸气压 | 0.0±0.6 mmHg at 25°C |
折射率 | 1.663 |
溶解性 | 可溶于:甲醇 |
储存条件 | 避免光 |
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符号 |
![]() ![]() GHS05, GHS06 |
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信号词 | Danger |
危害声明 | H301-H315-H318-H335 |
警示性声明 | P261-P280-P301 + P310-P305 + P351 + P338 |
个人防护装备 | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
危害码 (欧洲) | Xn |
风险声明 (欧洲) | 22-37/38-41 |
安全声明 (欧洲) | 26-39 |
危险品运输编码 | UN 2811 6.1 / PGIII |
海关编码 | 2933599090 |
Section1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE Product name: 2,4-Dichloro-5-iodopyrimidine Section2. HAZARDS IDENTIFICATION Classification of the substance or mixture According to Regulation (EC) No1272/2008 Acute toxicity, Oral (Category 3) Skin irritation (Category 2)
Serious eye damage (Category 1) Specific target organ toxicity - single exposure (Category 3) According to European Directive 67/548/EEC as amended. Harmful if swallowed. Irritating to respiratory system and skin. Risk of serious damage to eyes. Label elements Pictogram Signal wordDanger Hazard statement(s) H301Toxic if swallowed. H315Causes skin irritation. H318Causes serious eye damage. H335May cause respiratory irritation. Precautionary statement(s) P261Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray. P280Wear protective gloves/ eye protection/ face protection. P301 + P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/ physician. P305 + P351 + P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Hazard symbol(s) XnHarmful R-phrase(s) R22Harmful if swallowed. R37/38Irritating to respiratory system and skin. R41Risk of serious damage to eyes. S-phrase(s) S26In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39Wear eye/face protection. Other hazards - none Section3. COMPOSITION/INFORMATION ON INGREDIENTS Formula: C4HCl2IN2 Molecular Weight: 274,87 g/mol CAS-No.EC-No.Index-No.ClassificationConcentration 2,4-Dichloro-5-iodopyrimidine 13544-44-0--Acute Tox. 3; Skin Irrit. 2; Eye- Dam. 1; STOT SE 3; H301, H315, H318, H335 Xn, R22 - R37/38 - R41 For the full text of the H-Statements mentioned in this Section, see Section 16. Section4. FIRST AID MEASURES General advice Consult a physician. Show this safety data sheet to the doctor in attendance. If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. Section5. FIRE-FIGHTING MEASURES Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Special protective equipment for fire-fighters Wear self contained breathing apparatus for fire fighting if necessary. Section6. ACCIDENTAL RELEASE MEASURES Personal precautions Wear respiratory protection. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Methods and materials for containment and cleaning up Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal. Section7. HANDLING AND STORAGE Precautions for safe handling Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed. Normal measures for preventive fire protection. Conditions for safe storage Keep container tightly closed in a dry and well-ventilated place. Store in cool place. Handle and store under inert gas. Light sensitive. Section8. EXPOSURE CONTROLS/PERSONAL PROTECTION Personal protective equipment Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Hand protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Eye protection Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin and body protection Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Hygiene measures Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product. Section9. PHYSICAL AND CHEMICAL PROPERTIES Appearance Formsolid Safety data pH no data available Melting point65 - 69 °C Boiling pointno data available Flash pointno data available Ignition temperature no data available Lower explosion limit no data available Upper explosion limit no data available Water solubilityno data available Partition coefficient: log Pow: 2,635 n-octanol/water Section10. STABILITY AND REACTIVITY Chemical stability Stable under recommended storage conditions. Conditions to avoid no data available Materials to avoid Strong oxidizing agents Hazardous decomposition products Hazardous decomposition products formed under fire conditions. - Carbon oxides, nitrogen oxides (NOx), Hydrogen chloride gas, Hydrogen iodide Section11. TOXICOLOGICAL INFORMATION Acute toxicity no data available Skin corrosion/irritation no data available Serious eye damage/eye irritation no data available Respiratory or skin sensitization Prolonged or repeated exposure may cause allergic reactions in certain sensitive individuals. Germ cell mutagenicity no data available Carcinogenicity IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC. Reproductive toxicity no data available Specific target organ toxicity - single exposure Inhalation - May cause respiratory irritation. Specific target organ toxicity - repeated exposure no data available Aspiration hazard no data available Potential health effects InhalationMay be harmful if inhaled. Causes respiratory tract irritation. IngestionToxic if swallowed. SkinMay be harmful if absorbed through skin. Causes skin irritation. EyesCauses eye burns. Signs and Symptoms of Exposure To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. Additional Information RTECS: Not available Section12. ECOLOGICAL INFORMATION Toxicity no data available Persistence and degradability no data available Bioaccumulative potential no data available Mobility in soil no data available PBT and vPvB assessment no data available Other adverse effects no data available Section13. DISPOSAL CONSIDERATIONS Product Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Contaminated packaging Dispose of as unused product. Section14. TRANSPORT INFORMATION ADR/RID UN-Number: 2811 Class: 6.1Packing group: III Proper shipping name: TOXIC SOLID, ORGANIC, N.O.S. (2,4-Dichloro-5-iodopyrimidine) IMDG UN-Number: 2811 Class: 6.1Packing group: IIIEMS-No: F-A, S-A Proper shipping name: TOXIC SOLID, ORGANIC, N.O.S. (2,4-Dichloro-5-iodopyrimidine) Marine pollutant: No IATA UN-Number: 2811 Class: 6.1Packing group: III Proper shipping name: Toxic solid, organic, n.o.s. (2,4-Dichloro-5-iodopyrimidine) Section15. REGULATORY INFORMATION This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006. Section16. OTHER INFORMATION Text of H-code(s) and R-phrase(s) mentioned in Section 3 Acute Tox.Acute toxicity Eye Dam.Serious eye damage H301Toxic if swallowed. H315Causes skin irritation. H318Causes serious eye damage. H335May cause respiratory irritation. Skin Irrit.Skin irritation STOT SESpecific target organ toxicity - single exposure XnHarmful R22Harmful if swallowed. R37/38Irritating to respiratory system and skin. R41Risk of serious damage to eyes. Further information Copyright 2010 Co. License granted to make unlimited paper copies for internal use only. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Co., shall not be held liable for any damage resulting from handling or from contact with the above product. See reverse side of invoice or packing slip for additional terms and conditions of sale. |
~90% ![]() 13544-44-0 |
文献:SCHERING AKTIENGESELLSCHAFT Patent: WO2007/71455 A1, 2007 ; Location in patent: Page/Page column 146 ; WO 2007/071455 A1 |
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