3-(4-氯苯氧基)-1,2-丙二醇|3-(4-Chlorophenoxy)-1,2-propanediol|cas:104-29-0|西域试剂

3-(4-氯苯氧基)-1,2-丙二醇,3-(4-Chlorophenoxy)-1,2-propanediol,99.9%

产品编号：西域试剂-WR120219| CAS NO：104-29-0| MDL NO：MFCD00021990| 分子式：C₉H₁₁ClO₃| 分子量：202.64

Chlorphenesin 是一种可逆的抗原相关免疫抑制剂。Chlorphenesin 是一种抗菌和抗真菌剂，用于许多眼保健化妆品中。

本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用，

货号	价格	库存与货期
西域试剂-WR120219	￥90.00	杭州北京（现货）
西域试剂-WR120219	￥184.00	杭州北京（现货）
西域试剂-WR120219	￥312.00	杭州北京（现货）

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产品名称

3-(4-氯苯氧基)-1,2-丙二醇

英文名称

3-(4-Chlorophenoxy)-1,2-propanediol

CAS编号

104-29-0

产品描述

Chlorphenesin 是一种可逆的抗原相关免疫抑制剂。Chlorphenesin 是一种抗菌和抗真菌剂，用于许多眼保健化妆品中。

产品熔点

77-79°C

产品沸点

369.5±27.0 °C at 760 mmHg

产品密度

1.3±0.1 g/cm3

产品闪点

177.2±23.7 °C

精确质量

202.039673

PSA

49.69000

LogP

1.43

外观性状

白色至灰白色结晶粉末

蒸气压

0.0±0.9 mmHg at 25°C

折射率

1.565

溶解性数据

In Vitro:

DMSO : 100 mg/mL (493.51 mM; Need ultrasonic)

H₂O : ≥ 6.67 mg/mL (32.92 mM)

* "≥" means soluble, but saturation unknown.

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	4.9351 mL	24.6755 mL	49.3510 mL
5 mM	0.9870 mL	4.9351 mL	9.8702 mL
10 mM	0.4935 mL	2.4676 mL	4.9351 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用；以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

1.

请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% saline
Solubility: ≥ 2.5 mg/mL (12.34 mM); Clear solution

此方案可获得 ≥ 2.5 mg/mL (12.34 mM，饱和度未知) 的澄清溶液。
以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中，混合均匀；向上述体系中加入50 μL Tween-80，混合均匀；然后继续加入 450 μL生理盐水定容至 1 mL。
将 0.9 g 氯化钠，完全溶解于 100 mL ddH₂O 中，得到澄清透明的生理盐水溶液
2.

请依序添加每种溶剂： 10% DMSO 90% (20% SBE-β-CD in saline)
Solubility: ≥ 2.5 mg/mL (12.34 mM); Clear solution

此方案可获得 ≥ 2.5 mg/mL (12.34 mM，饱和度未知) 的澄清溶液。
以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中，混合均匀。
将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中，再用生理盐水定容至 10 mL，完全溶解，澄清透明
3.

请依序添加每种溶剂： 10% DMSO 90% corn oil
Solubility: ≥ 2.5 mg/mL (12.34 mM); Clear solution

此方案可获得 ≥ 2.5 mg/mL (12.34 mM，饱和度未知) 的澄清溶液，此方案不适用于实验周期在半个月以上的实验。
以 1 mL 工作液为例，取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL玉米油中，混合均匀。

*以上所有助溶剂都可在西域网站选购。

体外研究

氯苯那新（0.01,0.1,0.3%；30分钟暴露）显著降低人睑板腺上皮细胞（HMGECs）中Akt通路的活性，呈剂量依赖性。氯苯那新（0.1,0.3%；24小时）诱导永生化HMGECs（IHMGECs）变圆、萎缩、粘附不良、脱落，并显著减少IHMGECs的数量。

稳定性

避免与氧化物接触。

储存条件

储存于阴凉、通风的库房。远离火种、热源、水源。保持容器密封。应与氧化剂、还原剂分开存放，切忌混储。配备相应品种和数量的消防器材。储区应备有合适的材料收容泄漏物。

化学品安全说明书(MSDS)

下载MSDS

质检证书(COA)

相关产品

风险声明 (欧洲)	R20/21/22
安全声明 (欧洲)	S26-S36
海关编码	2909499000

Material Safety Data Sheet

Section1. Identiﬁcation of the substance
Chlorphenesin
Product Name:
Synonyms:3-(4-Chlorophenoxy)-1,2-Propanediol

Section2. Hazards identiﬁcation

Harmful by inhalation, in contact with skin, and if swallowed.
H315:Causes skin irritation
H319:Causes serious eye irritation
H335:May cause respiratory irritation
P261:Avoid breathing dust/fume/gas/mist/vapours/spray
Wear protective gloves/protective clothing/eye protection/face protection
P280:
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present
and easy to do – continue rinsing
P304+P340:IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
P405:Store locked up

Section3. Composition/information on ingredients.
Chlorphenesin
Ingredient name:
CAS number:104-29-0

Section4. First aid measures
Immediately wash skin with copious amounts of water for at least 15 minutes while removing
Skin contact:
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
ﬂushing of the eyes by separating the eyelids with ﬁngers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.
Ingestion:

Section5. Fire ﬁghting measures
In the event of a ﬁre involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualiﬁed
in the handling and use of potentially hazardous chemicals, who should take into account the ﬁre,
health and chemical hazard data given on this sheet.
Storage:Store in closed vessels.

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Not speciﬁed
Appearance:
Boiling point:No data
Melting point:No data
Flash point:No data
Density:No data
Molecular formula:C9H11ClO3
Molecular weight:202.6

Section10. Stability and reactivity
Conditions to avoid: Heat, ﬂames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, hydrogen chloride.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
Non-harzardous for air and ground transportation.

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.

SECTION 16 - ADDITIONAL INFORMATION
N/A