组织蛋白酶D 来源于牛脾脏, ≥2.0 units/mg protein,Cathepsin D, from bovine spleen

产品编号:西域试剂-WR141521| CAS NO:9025-26-7| MDL NO:MFCD00130749| 分子式:C15H16O3S| 分子量:276.351

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西域试剂-WR141521
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英文名称Cathepsin D, from bovine spleen
CAS编号9025-26-7
产品沸点432.4±45.0 °C at 760 mmHg
产品密度1.3±0.1 g/cm3
产品闪点215.3±28.7 °C
精确质量276.082001
LogP3.16
蒸气压0.0±1.1 mmHg at 25°C
折射率1.609
稳定性

Unit Definition One unit will produce an increase in A280 of 1.0 per min per mL at pH 3.0 at 37 °C measured as TCA-soluble products using hemoglobin as substrate (1 cm light path).

Physical form Lyophilized powder containing citrate buffer salts

Biochem/physiol Actions Cathepsin D is an endosomal-lysosomal aspartic protease implicated in breast cancer metastasis and Alzheimer’s disease. Lysosomal release of cathepsin D has been found to precede cytochrome c release and loss of membrane potential in apoptotic human foreskin fibroblasts. Cathepsin D levels in PC12 cells increase 12 to 24 hours after apoptosis is induced.

储存条件

-20°C密闭,避光,通风干燥处

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