成骨生长肽,Osteogenic Growth Peptide,98%
产品编号:西域试剂-WR142874| CAS NO:132996-61-3| 分子式:C68H110N22O18| 分子量:1523.753
Osteogenic Growth Peptide, OGP 是由 14 个氨基酸残基组成的多肽,是一种对骨髓损伤有系统性应答的促进因子,以 μM 级浓度存在于哺乳动物的血清中。
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产品名称 | 成骨生长肽 | ||||||||||||||||
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英文名称 | Osteogenic Growth Peptide | ||||||||||||||||
CAS编号 | 132996-61-3 | ||||||||||||||||
产品描述 | Osteogenic Growth Peptide, OGP 是由 14 个氨基酸残基组成的多肽,是一种对骨髓损伤有系统性应答的促进因子,以 μM 级浓度存在于哺乳动物的血清中。 | ||||||||||||||||
溶解性数据 | In Vitro: H2O : 100 mg/mL (65.63 mM; Need ultrasonic) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 | ||||||||||||||||
体外研究 | Osteogenic Growth Peptide (OGP) regulates proliferation, differentiation, and matrix mineralization in osteoblast lineage cells. The active portion of OGP, the OGP(10-14) region, is cleaved from the peptide and binds to the OGP receptor which activates the MAP kinase, the Src, and the RhoA pathways. Osteogenic Growth Peptide (OGP) is a native molecule with a primary structure identical to the C-terminus of histone H4, whose sequence contains a highly conserved 14-amino acid motif (NH2-ALKRQGRTLYGFGG-OH). This peptide is isolated from blood during osteogenic remodeling of post-ablation of marrow regeneration. The osteogenic growth peptide (OGP) and its C-terminal pentapeptide OGP(10-14) have been shown to stimulate the proliferation, differentiation, alkaline phosphatase activity and matrix mineralization of osteoblastic lineage cells. | ||||||||||||||||
储存条件 | 储存条件: -20°C 运输方式: 冰袋运输,根据产品的不同,可能会有相应调整。 |
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