BRD3308, 99%,BRD3308
产品编号:西域试剂-WR145355| CAS NO:1550053-02-5| 分子式:C15H14FN3O2| 分子量:287.294
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用途: | BRD3308 is a highly selective HDAC3 inhibitor with an IC50 of 54 nM. BRD3308 is 23-fold selectivity for HDAC3 over HDAC1 (IC50 of 1.26 μM) or HDAC2 (IC50 of 1.34 μM). BRD3308 suppresses pancreatic β-cell apoptosis induced by inflammatory cytokines or glucolipotoxic stress, and increases functional insulin release. BRD3308 activates HIV-1 transcription and disrupts HIV-1 latency. |
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储存条件: | -20°C,密闭,干燥 |
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