PTC596, 99%,PTC596
产品编号：西域试剂-WR147548| CAS NO：1610964-64-1| 分子式：C19H13F5N6| 分子量：420.330
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| 用途: | PTC596 is an orally active and selective B-cell-specific Moloney murine leukemia virus integration site 1 (BMI-1) inhibitor. PTC596 targets BMI1 expressed by both tumor cells and cancer stem cells (CSCs), and induces hyper-phosphorylation of BMI1, leading to its degradation. PTC596 downregulates MCL-1 and induces p53-independent mitochondrial apoptosis in acute myeloid leukemia progenitor cells. |
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| 储存条件: | -20°C，密闭，干燥 |
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