（6S）-2-氯-5,6,7,8,9,10-六氢环庚[b]吲哚-6-羧酰胺, ≥98% (chiral, HPLC)|CHIC-35|cas:848193-72-6|西域试剂

（6S）-2-氯-5,6,7,8,9,10-六氢环庚[b]吲哚-6-羧酰胺, ≥98% (chiral, HPLC),CHIC-35

产品编号：西域试剂-WR148821| CAS NO：848193-72-6| MDL NO：MFCD11045286| 分子式：C₁₄H₁₅ClN₂O| 分子量：262.73

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货号	包装	价格	库存与货期	购买量	操作
西域试剂-WR148821		￥2271.00	杭州北京（现货）

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用途:	CHIC-35 is cell-permeable, metabolically stable, and very potent inhibitor of SIRT1; IC50 of S-isomer is 60 nM; IC50 of mixed isomers is 124 nM. There is no inhibition of SIRT3 or HDAC. The IC50 for SIRT2 is 2.77 μM. Sirtuins are protein deacetylases, which represent a new class of histone deacetylases (HDAC) involved in gene silencing. SIRT modulators are potential therapeutics for cancer, diabetes, muscle differentiation, heart failure, neurodegeneration, and aging.
储存条件:	2-8°C
颜色:	固体
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