(2-苯基噻唑-4-基)甲醇, 98%,(2-Phenylthiazol-4-yl)methanol

产品编号:西域试剂-WR151427| CAS NO:23780-13-4| MDL NO:MFCD02682017| 分子式:C10H9NOS| 分子量:191.2500  

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英文名称(2-Phenylthiazol-4-yl)methanol
CAS编号23780-13-4
产品熔点65ºC
产品沸点372.2ºC at 760mmHg
产品密度1.264g/cm3
产品闪点178.9ºC
精确质量191.04000
PSA61.36000
LogP2.30240
蒸气压3.37E-06mmHg at 25°C
折射率1.629

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危害码 (欧洲) Xi: Irritant;
风险声明 (欧洲) R24/25
安全声明 (欧洲) 22-36/37/39
海关编码 2934100090
Name: (2-Phenyl-1 3-thiazol-4-yl)methanol 97% Material Safety Data Sheet
Synonym: 2-Phenyl-hydroxymethyl thiazol
CAS: 23780-13-4
Section 1 - Chemical Product MSDS Name:(2-Phenyl-1 3-thiazol-4-yl)methanol 97% Material Safety Data Sheet
Synonym:2-Phenyl-hydroxymethyl thiazol

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
23780-13-4 (2-Phenyl-1,3-thiazol-4-yl)methanol 97% unlisted
Hazard Symbols: None Listed.
Risk Phrases: 24/25

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Toxic in contact with skin and if swallowed.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
May cause respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 23780-13-4: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: cream
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 67 - 70 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C10H9NOS
Molecular Weight: 191

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Oxidizing agents, bases, acid chlorides.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, oxides of sulfur, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 23780-13-4 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
(2-Phenyl-1,3-thiazol-4-yl)methanol - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
No information available.
IMO
No information available.
RID/ADR
No information available.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
R 24/25 Toxic in contact with skin and if swallowed.
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 23780-13-4: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 23780-13-4 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 23780-13-4 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

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文献:BRISTOL-MYERS SQUIBB COMPANY; UNIVERSITÉ DE MONTRÉAL; BANVILLE, Jacques; RÉMILLARD, Roger; RUEDIGER, Edward H.; DEON, Daniel H.; GAGNON, Marc; DUBÉ, Laurence; GUY, Julia; PRIESTLEY, Eldon Scott; POSY, Shoshana L.; MAXWELL, Brad D.; WONG, Pancras C. Patent: WO2013/163279 A1, 2013 ; Location in patent: Paragraph 00145 ;

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文献:EP1228067 B1, ; Page 67 ;

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文献:Kwon, Il-Chun; Koh, Young Kook; Choi, Jun-Hyeak; Kim, Hong-Seok Journal of Heterocyclic Chemistry, 1996 , vol. 33, # 6 p. 1883 - 1886

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文献:Journal of the American Chemical Society, , vol. 65, p. 1667,1669

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文献:Journal of the American Chemical Society, , vol. 65, p. 1667,1669

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文献:Orr, David; Tolfrey, Alexandra; Percy, Jonathan M.; Frieman, Joanna; Harrison, Zoe A.; Campbell-Crawford, Matthew; Patel, Vipulkumar K. Chemistry - A European Journal, 2013 , vol. 19, # 29 p. 9655 - 9662

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文献:Archiv der Pharmazie, , vol. 343, # 7 p. 411 - 416

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