Tea polyphenol, 98%|Tea polyphenol|cas:84650-60-2|西域试剂

Tea polyphenol, 98%,Tea polyphenol

产品编号：西域试剂-WR173025| CAS NO：84650-60-2| 分子式：C₂₂H₁₈O₁₁| 分子量：458.372

Tea polyphenol 是茶中酚类化合物的总称。Tea polyphenol 具有抗氧化、抗癌、抑制细胞增殖、诱导细胞凋亡、延缓细胞周期、调节致癌物代谢等生物活性。

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货号	价格	库存与货期
西域试剂-WR173025	￥39.00	杭州北京（现货）
西域试剂-WR173025	￥58.00	杭州北京（现货）
西域试剂-WR173025	￥170.00	杭州北京（现货）
西域试剂-WR173025	￥728.00	杭州北京（现货）

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产品名称	Tea polyphenol, 98%
英文名称	Tea polyphenol
CAS编号	84650-60-2
产品描述	Tea polyphenol 是茶中酚类化合物的总称。Tea polyphenol 具有抗氧化、抗癌、抑制细胞增殖、诱导细胞凋亡、延缓细胞周期、调节致癌物代谢等生物活性。
产品沸点	909.1±65.0 °C at 760 mmHg
产品密度	1.9±0.1 g/cm3
产品闪点	320.0±27.8 °C
精确质量	458.084900
PSA	197.37000
LogP	2.08
外观性状	黄绿色自由流动粉末
蒸气压	0.0±0.3 mmHg at 25°C
折射率	1.857
溶解性数据	In Vitro: DMSO : 32.5 mg/mL (Need ultrasonic) In Vivo: 请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂： ——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用；以下溶剂前显示的百分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶 1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% saline Solubility: ≥ 3.25 mg/mL (Infinity mM); Clear solution 此方案可获得 ≥ 3.25 mg/mL (Infinity mM，饱和度未知) 的澄清溶液。以 1 mL 工作液为例，取 100 μL 32.5 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中，混合均匀；向上述体系中加入50 μL Tween-80，混合均匀；然后继续加入 450 μL生理盐水定容至 1 mL。将 0.9 g 氯化钠，完全溶解于 100 mL ddH₂O 中，得到澄清透明的生理盐水溶液 2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-β-CD in saline) Solubility: ≥ 3.25 mg/mL (Infinity mM); Clear solution 此方案可获得 ≥ 3.25 mg/mL (Infinity mM，饱和度未知) 的澄清溶液。以 1 mL 工作液为例，取 100 μL 32.5 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中，混合均匀。将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中，再用生理盐水定容至 10 mL，完全溶解，澄清透明 *以上所有助溶剂都可在西域网站选购。
稳定性	淡黄至茶褐色略带茶香的水溶液、灰白色粉状固体或结晶，具涩味。易溶于水、乙醇、乙酸乙酯，微溶于油脂。对热、酸较稳定，2%溶液加热至120℃并保持30min，无明显改变，在160℃：油脂中30rain降解20%，2%溶液在37℃下保持3天后，在pH值2～7范围内稳定，pH>7和光照下易氧化聚合。2%茶多酚在2%、5%和10%食盐溶液中于pH=6．5、室温下保存3天，其含量无变化。遇铁变绿黑色络合物。略有吸潮性，水溶液pH值为3～4，在碱性条件下易氧化褐变。
储存条件	-20°C

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危险品运输编码	NONH for all modes of transport
海关编码	3824909990

Section 1. Chemical Product and Company Identification
Green Tea Extract
Common Name/
Trade Name
Manufacturer
Commercial Name(s)

Synonym
Chemical Name
Chemical Family
Green Tea Extract

Section 4. First Aid Measures
Eye ContactCheck for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at
least 15 minutes. Cold water may be used. Get medical attention if irritation occurs.
Skin ContactWash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops.
Cold water may be used.
Serious Skin ContactNot available.
InhalationIf inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get
medical attention.
Serious InhalationNot available.
IngestionDo NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an
unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight
clothing such as a collar, tie, belt or waistband.
Serious IngestionNot available.

Section 5. Fire and Explosion Data
Flammability of the Product May be combustible at high temperature.
Auto-Ignition Temperature Not available.
Flash PointsNot available.
Flammable LimitsNot available.
Not available.
Products of Combustion
Fire Hazards in Presence of Slightly flammable to flammable in presence of open flames and sparks, of heat.
Various SubstancesNon-flammable in presence of shocks.
Explosion Hazards in Presence Risks of explosion of the product in presence of mechanical impact: Not available.
of Various SubstancesRisks of explosion of the product in presence of static discharge: Not available.
Fire Fighting MediaSMALL FIRE: Use DRY chemical powder.
and InstructionsLARGE FIRE: Use water spray, fog or foam. Do not use water jet.
Special Remarks onNot available.
Fire Hazards
Special Remarks on Explosion Not available.
Hazards

Section 6. Accidental Release Measures
Small SpillUse appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by
spreading water on the contaminated surface and dispose of according to local and regional authority
requirements.
Large Spill
Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water
on the contaminated surface and allow to evacuate through the sanitary system.
Green Tea Extract

Section 7. Handling and Storage
PrecautionsKeep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the
residue under a fume hood. Ground all equipment containing material. Do not breathe dust. Keep away from
incompatibles such as oxidizing agents.
StorageKeep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above 24°C (75.2°F).

Section 8. Exposure Controls/Personal Protection
Engineering ControlsUse process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
airborne contaminants below the exposure limit.
Personal ProtectionSafety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.
Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used
a Large Spillto avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist
BEFORE handling this product.
Exposure LimitsNot available.

Section 9. Physical and Chemical Properties
Physical state and appearance Solid.OdorCharacteristic. Tea-like
TasteNot available.
Molecular WeightNot available.
ColorBrown. (Light.)
pH (1% soln/water)Not available.
>176.67°C (350°F)
Boiling Point
Melting PointNot available.
Not available.
Critical Temperature
Specific GravityNot available.
Vapor PressureNot applicable.
Vapor DensityNot available.
VolatilityNot available.
Odor ThresholdNot available.
Water/Oil Dist. Coeff.Not available.
Ionicity (in Water)Not available.
Dispersion PropertiesSee solubility in water.
SolubilitySoluble in cold water, hot water.

Section 10. Stability and Reactivity Data
The product is stable.
Stability
Instability TemperatureNot available.
Conditions of InstabilityExcess heat, incompatible materials
Reactive with oxidizing agents.
Incompatibility with various
substances
Not available.
Corrosivity
Green Tea Extract
Incompatible with strong oxidizing agents.
Special Remarks on
Reactivity
Not available.
Special Remarks on
Corrosivity
PolymerizationWill not occur.

Section 11. Toxicological Information
Routes of EntryInhalation. Ingestion.
Toxicity to AnimalsLD50: Not available.
LC50: Not available.
Chronic Effects on Humans Not available.
Other Toxic Effects on
Slightly hazardous in case of skin contact (irritant), of inhalation.
Humans
Special Remarks onNot available.
Toxicity to Animals
Special Remarks onNot available.
Chronic Effects on Humans
Special Remarks on otherAcute Potential Heath Effects:
Toxic Effects on HumansSkin: May cause skin irritation.
Eyes: Dust may cause mechanical irritation to the eyes.
Inhalation: Dust may cause respiratory tract irritation.
Ingestion: Ingestion of large amounts may cause gastrointestinal tract irritation.
Chronic Potential Health Effects: no information found at this time.
The toxicological properties of this substance have not been fully investigated.

Section 12. Ecological Information
EcotoxicityNot available.
BOD5 and CODNot available.
Possibly hazardous short term degradation products are not likely. However, long term degradation products may
Products of Biodegradation
arise.
Toxicity of the ProductsNot available.
of Biodegradation
Special Remarks on theNot available.
Products of Biodegradation

Section 13. Disposal Considerations
Waste DisposalWaste must be disposed of in accordance with federal, state and local environmental
control regulations.

Section 14. Transport Information
DOT ClassificationNot a DOT controlled material (United States).
IdentificationNot applicable.
Special Provisions forNot applicable.
Transport
Green Tea Extract
DOT (Pictograms)

Section 15. Other Regulatory Information and Pictograms
No products were found.
Federal and State
Regulations
California
Proposition 65
Warnings
Other RegulationsNot available.
WHMIS (Canada) Not controlled under WHMIS (Canada).
Other Classifications
DSCL (EEC)This product is not classified according Not applicable.
to the EU regulations.
Health Hazard
HMIS (U.S.A.)1 National Fire Protection
1 Flammability
1 Association (U.S.A.)
Fire Hazard
1 0 Reactivity
Health
Reactivity
0
Specific hazard
Personal Protection
E
WHMIS (Canada)
(Pictograms)
DSCL (Europe)
(Pictograms)
TDG (Canada)
(Pictograms)
ADR (Europe)
(Pictograms)
Protective Equipment
Gloves.
Lab coat.
Dust respirator. Be sure to use an
approved/certified respirator or
equivalent.
Green Tea Extract

SECTION 16 - ADDITIONAL INFORMATION
N/A

[1]. Suzuki J, et al. Tea polyphenols regulate key mediators on inflammatory cardiovascular diseases. Mediators Inflamm. 2009;2009:494928.

[2]. Chen D, et al. Tea polyphenols, their biological effects and potential molecular targets. Histol Histopathol. 2008 Apr;23(4):487-96.

[3]. Mao X, et al. Oxidative stress-induced diseases and tea polyphenols. Oncotarget. 2017 Sep 14;8(46):81649-81661.