芦荟苷,Aloin,98%

产品编号:西域试剂-WR174713| CAS NO:8015-61-0| 分子式:C21H22O9| 分子量:418.394

Aloin (mixture of A&B) 是从芦荟中分离出来的蒽醌衍生物。Aloin (mixture of A&B) 具有多种生物活性,如抗炎、免疫、抗糖尿病、抗氧化、抗菌、抗真菌和抗肿瘤活性。Aloin (mixture of A&B) 是刺激性粒细胞基质金属蛋白酶 (MMPs) 的有效抑制剂。

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货号 包装 价格 库存与货期 购买量 操作
西域试剂-WR174713
160.00 杭州 北京(现货)
西域试剂-WR174713
390.00 杭州 北京(现货)
西域试剂-WR174713
1100.00 杭州 北京(现货)
西域试剂-WR174713
2800.00 杭州 北京(现货)

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产品名称芦荟苷
英文名称Aloin
CAS编号8015-61-0
产品描述Aloin (mixture of A&B) 是从芦荟中分离出来的蒽醌衍生物。Aloin (mixture of A&B) 具有多种生物活性,如抗炎、免疫、抗糖尿病、抗氧化、抗菌、抗真菌和抗肿瘤活性。Aloin (mixture of A&B) 是刺激性粒细胞基质金属蛋白酶 (MMPs) 的有效抑制剂。
产品沸点752.6±60.0 °C at 760 mmHg
产品密度1.6±0.1 g/cm3
产品闪点268.0±26.4 °C
精确质量418.126373
PSA167.91000
LogP1.86
蒸气压0.0±2.6 mmHg at 25°C
折射率1.741
溶解性pyridine: 50 mg/mL, clear, dark red
溶解性数据
In Vitro: 

DMSO : 100 mg/mL (239.01 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.3901 mL 11.9506 mL 23.9011 mL
5 mM 0.4780 mL 2.3901 mL 4.7802 mL
10 mM 0.2390 mL 1.1951 mL 2.3901 mL
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:

——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用; 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比;如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶

  • 1.

    请依序添加每种溶剂: 10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (5.98 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (5.98 mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 400 μL PEG300 中,混合均匀;向上述体系中加入50 μL Tween-80,混合均匀;然后继续加入 450 μL生理盐水定容至 1 mL。

    将 0.9 g 氯化钠,完全溶解于 100 mL ddH₂O 中,得到澄清透明的生理盐水溶液
  • 2.

    请依序添加每种溶剂: 10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (5.98 mM); Clear solution

    此方案可获得 ≥ 2.5 mg/mL (5.98 mM,饱和度未知) 的澄清溶液。

    以 1 mL 工作液为例,取 100 μL 25.0 mg/mL 的澄清 DMSO 储备液加到 900 μL 20% 的 SBE-β-CD 生理盐水水溶液中,混合均匀。

    将 2 g 磺丁基醚 β-环糊精加入 5 mL 生理盐水中,再用生理盐水定容至 10 mL,完全溶解,澄清透明
*以上所有助溶剂都可在西域网站选购。
靶点

MMPs

稳定性

常温常压下性质稳定。

储存条件

储存于阴凉干燥处。

相关文档

化学品安全说明书(MSDS)

下载MSDS

质检证书(COA)

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危害码 (欧洲) Xi
风险声明 (欧洲) R36/37/38
安全声明 (欧洲) S26;S36
WGK德国 3
海关编码 2938909090

Section 1. Chemical Product and Company Identification
Aloin
Common Name/
Trade Name
Aloin

Section 4. First Aid Measures
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least
Eye Contact
15 minutes. Get medical attention if irritation occurs.
Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops.
Skin Contact
Serious Skin ContactNot available.
InhalationIf inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get
medical attention.
Not available.
Serious Inhalation
Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an
Ingestion
unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight
clothing such as a collar, tie, belt or waistband.
Not available.
Serious Ingestion

Section 5. Fire and Explosion Data
Flammability of the Product May be combustible at high temperature.
Auto-Ignition Temperature Not available.
Not available.
Flash Points
Not available.
Flammable Limits
These products are carbon oxides (CO, CO2).
Products of Combustion
Fire Hazards in Presence of Slightly flammable to flammable in presence of heat.
Various Substances
Risks of explosion of the product in presence of mechanical impact: Not available.
Explosion Hazards in
Risks of explosion of the product in presence of static discharge: Not available.
Presence of Various
Substances
SMALL FIRE: Use DRY chemical powder.
Fire Fighting Media
LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
and Instructions
Material in powder form, capable of creating a dust explosion. As with most organic solids, fire is possible at elevated
Special Remarks on
temperatures
Fire Hazards
Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust
Special Remarks on
explosion hazard.
Explosion Hazards

Section 6. Accidental Release Measures
Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading
Small Spill
water on the contaminated surface and dispose of according to local and regional authority requirements.
Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on
Large Spill
the contaminated surface and allow to evacuate through the sanitary system.
Aloin

Section 7. Handling and Storage
Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not
Precautions
breathe dust.
Keep container tightly closed. Keep container in a cool, well-ventilated area.
Storage

Section 8. Exposure Controls/Personal Protection
Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
Engineering Controls
recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
airborne contaminants below the exposure limit.
Personal ProtectionSafety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.
Personal Protection in Case Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to
avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE
of a Large Spill
handling this product.
Exposure LimitsNot available.

Section 9. Physical and Chemical Properties
Solid. (Powdered solid.)Not available.
Physical state andO dor
appearance
Bitter.
Taste
418.39 g/mole
Molecular Weight
Yellowish-brown. Yellow.
Color
Not available.
pH (1% soln/water)
Not available.
Boiling Point
148°C (298.4°F)
Melting Point
Not available.
Critical Temperature
Not available.
Specific Gravity
Not applicable.
Vapor Pressure
Not available.
Vapor Density
Not available.
Volatility
Not available.
Odor Threshold
Not available.
Water/Oil Dist. Coeff.
Not available.
Ionicity (in Water)
Not available.
Dispersion Properties
Not available.
Solubility

Section 10. Stability and Reactivity Data
The product is stable.
Stability
Not available.
Instability Temperature
Conditions of Instability Excess heat.
Incompatibility with various Not available.
substances
Non-corrosive in presence of glass.
Corrosivity
Aloin
Not available.
Special Remarks on
Reactivity
Not available.
Special Remarks on
Corrosivity
Will not occur.
Polymerization

Section 11. Toxicological Information
Inhalation. Ingestion.
Routes of Entry
Toxicity to AnimalsLD50: Not available.
LC50: Not available.
Chronic Effects on Humans Not available.
Slightly hazardous in case of skin contact (irritant), of ingestion, of inhalation.
Other Toxic Effects on
Humans
Not available.
Special Remarks on
Toxicity to Animals
Not available.
Special Remarks on
Chronic Effects on Humans
Acute Potential Health Effects:
Special Remarks on other
Skin: It can cause skin irritation.
Toxic Effects on Humans
Eyes: It can cause eye irritation.
Inhalation: It may cause respiratory tract irritation.
Ingeston: It has laxative properties and increases the perstaltic contractions in the colon. It also prevents the colon
from re-absorbing water from the gastrointestinal tract, which leads to softer stools. Ingestion of large amounts may
cause abdominal pain, diarrhea, an electrolyte imbalance.

Section 12. Ecological Information
Not available.
Ecotoxicity
Not available.
BOD5 and COD
Products of Biodegradation Possibly hazardous short term degradation products are not likely. However, long term degradation products may
arise.
The product itself and its products of degradation are not toxic.
Toxicity of the Products
of Biodegradation
Not available.
Special Remarks on the
Products of Biodegradation

Section 13. Disposal Considerations
Waste must be disposed of in accordance with federal, state and local environmental control
Waste Disposal
regulations.

Section 14. Transport Information
Not a DOT controlled material (United States).
DO T Cl assi fi cati on
Not applicable.
Identification
Not applicable.
Special Provisions for
Transport
Aloin
DO T (Pi ctograms)

Section 15. Other Regulatory Information and Pictograms
TSCA 8(b) inventory: Aloin
Federal and State
Regulations
California prop. 65: This product contains the following ingredients for which the State of California has found to
California
cause cancer which would require a warning under the statute: No products were found.
Proposition 65
Warnings
California prop. 65: This product contains the following ingredients for which the State of California has found to
cause birth defects which would require a warning under the statute: No products were found.
Other RegulationsEINECS: This product is not on the European Inventory of Existing Commercial Chemical Substances.
Canada: Listed on Canadian Domestic Substance List (DSL).
China: Not listed on National Inventory.
Japan: Not listed on National Inventory (ENCS).
Korea: Not listed on National Inventory (KECI).
Philippines: Listed on National Inventory (PICCS).
Australia: Listed on AICS.
WHMIS (Canada) Not controlled under WHMIS (Canada).
Other Classifications
This product is not classified according Not applicable.
DSCL (EEC)
to the EU regulations.
Health Hazard
HMIS (U.S.A.)1 National Fire Protection
1 Flammability
1 Association (U.S.A.)
Fire Hazard
1 0 Reactivity
Health
Reactivity
0
Specific hazard
Personal Protection
E
WHMIS (Canada)
(Pictograms)
DSCL (Europe)
(Pictograms)
TDG(Canada)
(Pictograms)
ADR (Europe)
(Pictograms)
Protective Equipment
Gloves.
Aloin
Lab coat.
Dust respirator. Be sure to use an
approved/certified respirator or equivalent.


SECTION 16 - ADDITIONAL INFORMATION
N/A

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