3-氯-L-丙氨酸, 98%|3-Chloro-L-alanine|cas:2731-73-9|西域试剂

3-氯-L-丙氨酸, 98%,3-Chloro-L-alanine

产品编号：西域试剂-WR183380| CAS NO：2731-73-9| MDL NO：MFCD00046536| 分子式：C₃H₆ClNO₂| 分子量：123.54

β-Chloro-L-alanine是抑制多种酶的抑菌氨基酸类似物，抑制包括苏氨酸脱氨酶和丙氨酸消旋酶。

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货号	价格	库存与货期
西域试剂-WR183380	￥196.00	杭州北京（现货）
西域试剂-WR183380	￥884.00	杭州北京（现货）
西域试剂-WR183380	￥4339.00	杭州北京（现货）

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英文名称

3-Chloro-L-alanine

CAS编号

2731-73-9

产品描述

β-Chloro-L-alanine是抑制多种酶的抑菌氨基酸类似物，抑制包括苏氨酸脱氨酶和丙氨酸消旋酶。

产品熔点

156 °C

产品沸点

243.6±30.0 °C at 760 mmHg

产品密度

1.4±0.1 g/cm3

产品闪点

101.1±24.6 °C

精确质量

123.008705

PSA

63.32000

LogP

-0.13

外观性状

白色结晶粉末

蒸气压

0.0±1.0 mmHg at 25°C

折射率

1.499

溶解性

可溶

溶解性数据

In Vitro:

H₂O : ≥ 30 mg/mL (242.84 mM)

* "≥" means soluble, but saturation unknown.

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	8.0945 mL	40.4727 mL	80.9454 mL
5 mM	1.6189 mL	8.0945 mL	16.1891 mL
10 mM	0.8095 mL	4.0473 mL	8.0945 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用；以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

1.

请依序添加每种溶剂： PBS
Solubility: 50 mg/mL (404.73 mM); Clear solution; Need ultrasonic

*以上所有助溶剂都可在西域网站选购。

靶点

Bacterial

体外研究

β-氯-L-丙氨酸可以抑制苏氨酸脱氨酶，支链氨基酸转氨酶（转氨酶B），L-天冬氨酸 - 脱羧酶，丙氨酸消旋酶和可能的O-乙酰丝氨酸硫氢化酶。 β-氯-L-丙氨酸可逆地抑制大肠杆菌K-12丙氨酸 - 缬氨酸转氨酶，转氨酶C.这种抑制作用与转氨酶B的抑制一起，解释了大肠杆菌在存在的情况下对异亮氨酸加缬氨酸的需求。 β氯-L-丙氨酸。如果将异亮氨酸和缬氨酸添加到培养基中并且假定生长要求是由于转氨酶B的抑制，那么鼠伤寒沙门氏菌LT2将在BCA存在下生长。

储存条件

密封储存，储存于阴凉、干燥的库房。

化学品安全说明书(MSDS)

下载MSDS

质检证书(COA)

相关产品

危害码 (欧洲)	C
安全声明 (欧洲)	24/25
海关编码	2922499990

Name:	3-Chloro-L-alanine Material Safety Data Sheet
Synonym:
CAS:	2731-73-9

Section 1 - Chemical Product MSDS Name:3-Chloro-L-alanine Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
2731-73-9	3-Chloro-L-alanine		unlisted

Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION

EMERGENCY OVERVIEW
Not available.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
May cause respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 2731-73-9: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Powder
Color: Not available.
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C3H6ClNO2
Molecular Weight: 123.5005

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Not available.
Incompatibilities with Other Materials:
Not available.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 2731-73-9 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
3-Chloro-L-alanine - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION

Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 2731-73-9: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 2731-73-9 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 2731-73-9 is not listed on the TSCA inventory.
It is for research and development use only.

SECTION 16 - ADDITIONAL INFORMATION
N/A

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