RYANODINE ,6-(1B1;,5aB2;,8aB2;,9-pentahydroxy-7B2;-isopropyl-2B2;,5B2;,8B2;-trimethylperhydro-8bB1;,9-epoxy-5,8-ethanocyclopenta[1,2-b]indenyl) pyrrole-2-carboxylate ,≥99%
产品编号:Bellancom-B245276| CAS NO:15662-33-6| 分子式:C25H35NO9| 分子量:493.5467
Ryanodine是可渗透细胞的兰尼碱受体调节剂。 根据其浓度,Ryanodine可以刺激或抑制Ryanodine介导的Ca2+ 释放。 在Ryania speciosa中发现的有毒二萜。
本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用,
产品名称 | RYANODINE |
---|---|
英文名称 | 6-(1B1;,5aB2;,8aB2;,9-pentahydroxy-7B2;-isopropyl-2B2;,5B2;,8B2;-trimethylperhydro-8bB1;,9-epoxy-5,8-ethanocyclopenta[1,2-b]indenyl) pyrrole-2-carboxylate |
CAS编号 | 15662-33-6 |
产品描述 | Ryanodine是可渗透细胞的兰尼碱受体调节剂。 根据其浓度,Ryanodine可以刺激或抑制Ryanodine介导的Ca2+ 释放。 在Ryania speciosa中发现的有毒二萜。 |
产品沸点 | 714.2±60.0 °C at 760 mmHg |
产品密度 | 1.6±0.1 g/cm3 |
产品闪点 | 385.7±32.9 °C |
精确质量 | 493.231171 |
PSA | 172.70000 |
LogP | 3.86 |
外观性状 | 白色固体 |
蒸气压 | 0.0±2.4 mmHg at 25°C |
折射率 | 1.685 |
靶点 |
Ryanodine receptor |
体内研究 | Ryanodine(100-5000 nM,30-120分钟)以剂量相关的方式不可逆地抑制快肌和慢肌的抽搐和强直张力。在浓度高于250 nM时,兰尼碱诱导缓慢发展的剂量依赖性挛缩,不能被5 mMCo2 +阻断。 |
储存条件 | 库房通风低温干燥,与食品原料分开储运 |
相关文档
化学品安全说明书(MSDS)
下载MSDS质检证书(COA)
相关产品
符号 |
![]() ![]() GHS07, GHS09 |
---|---|
信号词 | Warning |
危害声明 | H302 + H312-H410 |
警示性声明 | P273-P280-P501 |
危害码 (欧洲) | Xn: Harmful;N: Dangerous for the environment; |
风险声明 (欧洲) | R21/22 |
安全声明 (欧洲) | 36/37-60-61 |
危险品运输编码 | UN 3077 9 |
RTECS号 | VM4025000 |
Synonym:Ryanadol; 3-(1 H-pyrrole-2-carboxylate Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: 20/22 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Harmful by inhalation and if swallowed. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. Ingestion: Harmful if swallowed. Inhalation: Harmful if inhaled. The toxicological properties of this substance have not been fully investigated. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Deep freeze (below -20C). Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 15662-33-6: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: off-white Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 219-220 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: insoluble Specific Gravity/Density: Molecular Formula: C25H35NO9 Molecular Weight: 493.2463 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Will not occur. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 15662-33-6: VM4025000 LD50/LC50: CAS# 15662-33-6: Oral, mouse: LD50 = 650 mg/kg; Oral, rabbit: LD50 = 650 mg/kg; Oral, rat: LD50 = 750 mg/kg; Skin, rabbit: LD50 = >4 gm/kg. Carcinogenicity: Ryanodine - Not listed by ACGIH, IARC, or NTP. Other: See actual entry in RTECS for complete information. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA No information available. IMO No information available. RID/ADR No information available. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XN Risk Phrases: R 20/22 Harmful by inhalation and if swallowed. Safety Phrases: S 37/39 Wear suitable gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 15662-33-6: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 15662-33-6 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 15662-33-6 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A |
~3% ![]() 15662-33-6 |
文献:Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , p. 1011 - 1016 |
上游产品 1 | |
---|---|
下游产品 6 | |