紫云英苷|cas:480-10-4|西域试剂

紫云英苷,分析标准品,HPLC≥99%

产品编号：西域质检-TM58168| CAS NO：480-10-4| 分子式：C₂₁H₂₀O₁₁| 分子量：448.377

Astragalin (Astragaline) 是一种具有抗炎、抗氧化、抗癌、抑菌活性的黄酮类化合物。Astragalin 抑制癌细胞增殖和迁移，诱导细胞凋亡 (apoptosis)。Astragalin 具有口服活性，具有保护神经和心脏，抵抗骨质疏松的作用。

本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用，

货号	包装	价格	库存与货期	购买量	操作
西域质检-TM58168		￥960.00	杭州北京（现货）
西域质检-TM58168		￥2900.00	杭州北京（现货）

增值税发票√顺丰快递√订货电话：18601927057

紫云英苷

Reference Material

This certificate is designed in accordance with ISO 17034 and ISO Guide 31. This reference material (RM) was designed,produced and verified in accordance with ISO/IEC 17025, ISO 17034 and a registered quality management system ISO 9001.

Product Name(产品名称) Astragalin(紫云英苷)

Product Code(产品编号) 724343-20mg

Lot Number(产品批号) -

CAS No. 480-10-4

Mol. Weight(分子量) 448.38

Mol. Formula(分子式) C₂₁H₂₀O₁₁

Melting Point(熔点) N/A

Expiry Date(失效日期) -

Boiling point(沸点) N/A

Appearance(外观) Yellow Solid
(黄色固体)_____

Storage Temp(存储条件) (2~8)℃,dark
冷藏(2~8)℃避光

C E R T I F I E D

Purity

99.9%

C E R T I F I E D

Expanded Uncertainty (U)

0.8%

Uncertainty

The certified value(s) and uncertainty(ies) are determined in accordance with ISO 17034 with an 95% confidence level(k=2). Uncertainty is based on the Total Combined Uncertainty, including uncertainties of characterisation, homogeneity and stability testing. Stability values are based on real evidence opposed to simulation.

Traceability

The balances used for gravimetric measurements are calibrated with weights traceable to the national standards. The calibration of the balances is verified annually by an external accredited calibration service. This analysis method has been verified using an approach consistent with ISO 17034:2016 & ISO 17025:2017.

CERTIFICATE ON	QC SIGNATURE
-		RM Release

Method of Identification

HPLC

Method of Identification

HPLC

Intended Use

This RM is intended for use in a laboratory as a calibration and quality control standard or in method development for analytical techniques.

Storage

This reference material meets the specification stated in this certificate until the expiry date, provided it is stored unopened at the recommended temperature here in. If storage after opening is necessary, the RM should be tightly closed and kept from light and moisture.

Hazards

Read Material Safety Data Sheet (MSDS) and understand any potential hazard(s) prior to the use of this product. All chemicals should be considered potentially hazardous in nature and should only be handled by qualified personnel using established good laboratory practices.

Homogeneity

Random replicate samples of the final packaged RM have been analysed to prove homogeneity compliant with ISO 17034.

Instructions for use

It is recommended to use 1 mg as the minimum sample size and if less material is used, to increase the certified uncertainty by a factor of two for half sample and four for a quarter of sample.Visit the support section of our website technology videos and frequently asked questions.

化学品安全说明书(MSDS)

下载MSDS

质检证书(COA)

安全声明 (欧洲)	22
危险品运输编码	NONH for all modes of transport
RTECS号	DJ3080000

1. 物质的识别

产品名：	Astragalin
CAS号：	480-10-4
制造商/供应商：	西域试剂网站：www.hzbp.cn 邮件：13911702513@139.com

2. 合成/成分数据

产品名：	Astragalin
别名：	Astragaline; 3-Glucosylkaempferol; Kaempferol 3-β-D-glucopyranoside
分子式：	C21H20O11
分子量：	448.38

3. 急救措施

吸入后：	如果吸入，移至空气新鲜处，如果呼吸困难，给输氧，如呼吸停止，给予人工呼吸。
皮肤接触后：	用大量的水冲洗，移除污染的衣服和鞋子。
眼睛接触后：	检查并取下隐形眼镜，并用大量的水冲洗；呼叫医生。
吞食后：	如果吞食，用大量纯净水漱口；呼叫医生。

4. 消防措施

适当的灭火剂：	雾状水，二氧化碳，干粉或泡沫。
防护设备：	穿戴自给式呼吸器和防护服，以防止与皮肤和眼睛接触。

5. 泄漏应急处理

安全防范措施：	封锁泄漏区域；穿戴自给式呼吸器，防护服和厚橡胶手套。
清洁/收集措施：	使用液体粘合原料（硅藻土，通用粘合剂）吸取精细粉末；使用酒精擦洗表面和设备除去污渍；根据第11条处理被污染的材料。

6. 处理和储存

安全处理说明：	避免吸入和接触皮肤，眼睛及衣物；材料可能略微具有刺激性。
储存：	粉末型式 -20°C 3年；4°C 2年溶于溶剂 -80°C 6个月；-20°C 1个月

7. 接触控制和个人防护

呼吸设备：	NIOSH / MSHA认可的呼吸器。
双手保护：	耐化学腐蚀的橡胶手套。
眼睛防护：	化学安全护目镜。

8. 稳定性和反应活性

稳定性：	按照说明存储是稳定的；避免强氧化剂。
热分解/其他要避免的情况：	避免光和热。

9. 毒性资料

急性毒性：	无可用资料。
主要刺激性影响：	无可用资料。
在皮肤上：	无可用资料。
对眼睛：	无可用资料；可能具有刺激性。

10. 生态资料

一般注意事项：

无可用资料。

11. 废弃处置

按照所在国家，省份，县市和地方的法规处置。

12. 运输信息

正确的运输名称：	无
非危险品运输：	这种物质被视为非危险品运输。

13. 法规信息

尚未有针对此产品作出的化学安全性评估。

14. 其他信息

上游产品 6
133-89-1 520-18-3 152390-63-1 56317-05-6
23405-70-1 96333-59-4
下游产品 8
59-23-4 520-18-3 10257-28-0 99-96-7
50-99-7 2280-44-6 492-61-5 108-73-6

69. [3.612] Yingping Shi et al."Pickering emulsion co-stabilised by cellulose nanocrystals and astragalin/tangeretin: effect of environmental factors."INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY.2023 Feb;:

68. [7.425] Jingna Yan et al."Characterization of triterpenoids as possible bitter-tasting compounds in teas infected with bird’s eye spot disease."FOOD RESEARCH INTERNATIONAL.2023 Feb;:112643

67. [2.586] Mailing Zou et al."Profiling aromatic constituents of Chimonanthus nitens Oliv. leaf granule using mass spectrometry."RAPID COMMUNICATIONS IN MASS SPECTROMETRY.2023 Jan;:e9481

66. [4.342] MeiLing Han et al."Analysis of physicochemical and antioxidant properties of Malus spp. petals reveals factors involved in flower color change and market value."SCIENTIA HORTICULTURAE.2023 Feb;310:111688

65. [6.208] Yu Yao et al."A Novel 3-O-rhamnoside: 2″-O-xylosyltransferase Responsible for Terminal Modification of Prenylflavonol Glycosides in Epimedium pubescens Maxim.."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2022 Jan;23(24):16050

64. [4.927] Qinhua Zheng et al."Protective Effect of Flavonoids from Mulberry Leaf on AAPH-Induced Oxidative Damage in Sheep Erythrocytes."MOLECULES.2022 Jan;27(21):7625

63. [6.317] Mengqi Liu et al."Structure-Guided Discovery of Food-derived GABA-T Inhibitors as Hunter for Anti-anxiety Compounds."Food & Function.2022 Nov;:

62. [IF=4.125] Fuhao Tang et al."Screening Strategy for Predominant phenolic components of digestive enzyme inhibitors in Passion Fruit Peel Extracts on Simulated Gastrointestinal Digestion."JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE.2022 Oct;:

61. [IF=4.658] Hongzhen Wang et al."Induction, Proliferation, Regeneration and Kinsenoside and Flavonoid Content Analysis of the Anoectochilus roxburghii (Wall.) Lindl Protocorm-like Body."Plants-Basel.2022 Jan;11(19):2465

60. [IF=6.698] Shasha Tian et al."Mixed computational-experimental study to reveal the anti-metastasis and anti-angiogenesis effects of Astragalin in human breast cancer."COMPUTERS IN BIOLOGY AND MEDICINE.2022 Nov;150:106131

59. [IF=8.005] Wu Qing-Wen et al."Rhamnosyltransferases Involved in the Biosynthesis of Flavone Rutinosides in Chrysanthemum Species."PLANT PHYSIOLOGY.2022 Aug;:

58. [IF=4.342] Liyang Wu et al."Chemical compositions of raspberry leaves influenced by growth season, cultivars and leaf position."SCIENTIA HORTICULTURAE.2022 Oct;304:111349

57. [IF=5.318] Zhuoya Xiang et al."Assessment of free and bound phenolics in the flowers and floral organs of two Camellia species flower and their antioxidant activities."Food Bioscience.2022 Oct;49:101905

56. [IF=6.486] Ping Zheng et al."Comparative analyses of American and Asian lotus genomes reveal insights into petal color, carpel thermogenesis and domestication."PLANT JOURNAL. 2022 Apr 01

55. [IF=5.34] Mingliang Gao et al."Discovery of processing-associated Q-marker of carbonized traditional Chinese medicine: an integrated strategy of metabolomics, systems pharmacology and in vivo high-throughput screening model."PHYTOMEDICINE. 2022 May;:154152

54. [IF=5.396] Xiaoqin Zhang et al."Chimonanthus salicifolius attenuated vascular remodeling by alleviating endoplasmic reticulum stress in spontaneously hypertensive rat."Food & Function. 2022 May;:

53. [IF=6.953] Yanqing Yang et al."The hypoglycemic and hypolipemic potentials of Moringa oleifera leaf polysaccharide and polysaccharide-flavonoid complex."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. 2022 May;:

52. [IF=4.294] Yang Hu et al."Astragalin attenuates AlCl3/D-galactose-induced aging-like disorders by inhibiting oxidative stress and neuroinflammation."NEUROTOXICOLOGY. 2022 Jul;91:60

51. [IF=5.34] Dong Shao et al."Identification of the active compounds and functional mechanisms of Jinshui Huanxian formula in pulmonary fibrosis by integrating serum pharmacochemistry with network pharmacology."PHYTOMEDICINE. 2022 Jul;102:154177

50. [IF=3.24] YanShou Shi et al."Seasonal variation influences flavonoid biosynthesis path and content, and antioxidant activity of metabolites in Tetrastigma hemsleyanum Diels & Gilg."PLoS One. 2022 Apr;17(4):e0265954

49. [IF=3.373] Yiyuan Luo et al."Quality evaluation of Tetrastigma hemsleyanum different parts based on quantitative analysis of 42 bioactive constituents combined with multivariate statistical analysis."PHYTOCHEMICAL ANALYSIS. 2022 Apr 05

48. [IF=6.576] Guowei Man et al."Profiling Phenolic Composition in Pomegranate Peel From Nine Selected Cultivars Using UHPLC-QTOF-MS and UPLC-QQQ-MS."Front Nutr. 2021; 8: 807447

47. [IF=1.312] Xiaoran Zhao et al."Discrimination of Cuscuta chinensis Lam. and Cuscuta japonica Choisy based on a combination of chemometrics and fingerprint classification."Journal Of Liquid Chromatography & Related Technologies. 2022 Jan 09

46. [IF=6.057] Qi Tong et al.Biosynthesis-based spatial metabolome of Salvia miltiorrhiza Bunge by combining metabolomics approaches with mass spectrometry-imaging.Talanta. 2021 Nov;:123045

45. [IF=1.908] Lin Zheng et al."Comparative pharmacokinetics of quercitrin, astragalin, afzelin and taxifolin in plasma after oral administration of Polygonum orientale inflorescence in sham-operated and myocardial ischemia–reperfusion injury rats."Xenobiotica. 2020;50

44. [IF=2.19] Sheng-xiang Yang et al."Extraction of flavonoids from Cyclocarya paliurus (Juglandaceae) leaves using ethanol/salt aqueous two-phase system coupled with ultrasonic."J Food Process Pres. 2020 Jun;44(6):e14469

43. [IF=2.245] Hu Xuequan et al."Anti-inflammatory Effect of Astragalin and Chlorogenic Acid on Escherichia coli-Induced Inflammation of Sheep Endometrial Epithelium Cells."Front Vet Sci. 2020 Apr;7:201

42. [IF=2.633] Yanni Cao et al."Seasonal Variation in Phenolic Compounds and Antioxidant Activity in Leaves of Cyclocarya paliurus (Batal.) Iljinskaja."Forests. 2019 Aug;10(8):624

41. [IF=3.167] Ya Wu et al."Anti-obesity effect of Liupao tea extract by modulating lipid metabolism and oxidative stress in high-fat-diet-induced obese mice."J Food Sci. 2021 Jan;86(1):215-227

40. [IF=4.098] Chunlin Li et al."Discrimination of white teas produced from fresh leaves with different maturity by near-infrared spectroscopy."Spectrochim Acta A. 2020 Feb;227:117697

39. [IF=4.169] Zhang Zhen et al."Foliar Spraying of 6-Benzylaminopurine Promotes Growth and Flavonoid Accumulation in Mulberry (Morus alba L.)."Journal Of Plant Growth Regulation. 2021 Jul 15

38. [IF=4.24] Nana Li et al."Characterization of phenolic compounds and anti-acetylcholinase activity of coconut shells."Food Biosci. 2021 Aug;42:101204

37. [IF=4.36] Mingliang Gao et al."Evaluation of VEGF mediated pro-angiogenic and hemostatic effects and chemical marker investigation for Typhae Pollen and its processed product."J Ethnopharmacol. 2021 Mar;268:113591

36. [IF=4.36] Li Lin et al."Study on the alleviation of Fengshi Gutong capsule on rheumatoid arthritis through integrating network pharmacology and experimental exploration."J Ethnopharmacol. 2021 Nov;280:114471

35. [IF=4.759] Fengli Chen et al."Magnetically stabilized bed packed with synthesized magnetic silicone loaded with ionic liquid particles for efficient enrichment of flavonoids from tree peony petals."J Chromatogr A. 2020 Feb;1613:460671

34. [IF=4.952] Yuxin Hao et al."Stability and mechanism of phenolic compounds from raspberry extract under in vitro gastrointestinal digestion."Lwt Food Sci Technol. 2021 Mar;139:110552

33. [IF=5.279] Qinggang Yin et al."Identification of Specific Glycosyltransferases Involved in Flavonol Glucoside Biosynthesis in Ginseng Using Integrative Metabolite Profiles, DIA Proteomics, and Phylogenetic Analysis."J Agr Food Chem. 2021;69(5):1714–1726

32. [IF=5.645] Zhang-Zhen Bai et al."Comparative investigation on metabolites and biological activities of Paeonia ostii stamens from different geographical regions of China."Ind Crop Prod. 2021 Nov;172:114038

31. [IF=5.81] Mu Jianfei et al."Determination of Polyphenols in Ilex kudingcha and Insect Tea (Leaves Altered by Animals) by Ultra-high-performance Liquid Chromatography-Triple Quadrupole Mass Spectrometry (UHPLC-QqQ-MS) and Comparison of Their Anti-Aging Effects."Fro

30. [IF=6.306] Wei Yang et al."Liquid chromatography–mass spectrometry-based metabolomics analysis of flavonoids and anthraquinones in Fagopyrum tataricum L. Gaertn. (tartary buckwheat) seeds to trace morphological variations."Food Chem. 2020 Nov;331:127354

29. [IF=3.743] Xiao-Xu Han et al."Protective effects of Astragalin on spermatogenesis in streptozotocin-induced diabetes in male mice by improving antioxidant activity and inhibiting inflammation."Biomed Pharmacother. 2019 Feb;110:561

28. [IF=4.098] Chunlin Li et al."Rapid and non-destructive discrimination of special-grade flat green tea using Near-infrared spectroscopy."Spectrochim Acta A. 2019 Jan;206:254

27. [IF=4.171] Chanmin Liu et al."Flavonoid-Rich Extract of Paulownia fortunei Flowers Attenuates Diet-Induced Hyperlipidemia, Hepatic Steatosis and Insulin Resistance in Obesity Mice by AMPK Pathway."Nutrients. 2017 Sep;9(9):959

26. [IF=4.411] Yanni Cao et al."Chemical Fingerprint and Multicomponent Quantitative Analysis for the Quality Evaluation of Cyclocarya paliurus Leaves by HPLC–Q–TOF–MS."Molecules. 2017 Nov;22(11):1927

25. [IF=4.451] Jianzhong Zhu et al."In-vitro inhibitory effects of flavonoids in Rosa roxburghii and R. sterilis fruits on α-glucosidase: Effect of stomach digestion on flavonoids alone and in combination with acarbose."J Funct Foods. 2019 Mar;54:13

24. Yang, Jing, et al. "Comparisons of the active components in four unripe raspberry extracts and their activites." Food Science and Technology 39 (2019): 632-639.https://doi.org/10.1590/fst.27418

23. Gao, Mingliang, et al. "Evaluation of VEGF mediated pro-angiogenic and hemostatic effects and chemical marker investigation for Typhae Pollen and its processed product." Journal of Ethnopharmacology 268 (2021): 113591.https://doi.org/10.1016/j.jep.2020.113

22. Yang, Wei, et al. "Liquid chromatography–mass spectrometry-based metabolomics analysis of flavonoids and anthraquinones in Fagopyrum tataricum L. Gaertn.(tartary buckwheat) seeds to trace morphological variations." Food chemistry 331 (2020): 127354.https:/

21. Wu, Ya, et al. "Anti‐obesity effect of Liupao tea extract by modulating lipid metabolism and oxidative stress in high‐fat‐diet‐induced obese mice." Journal of Food Science 86.1 (2021): 215-227.

20. Cao, Yanni, et al. "Chemical fingerprint and multicomponent quantitative analysis for the quality evaluation of Cyclocarya paliurus leaves by HPLC–Q–TOF–MS." Molecules 22.11 (2017): 1927.https://doi.org/10.3390/molecules22111927

19. Liu, Chanmin, et al. "Flavonoid-rich extract of Paulownia fortunei flowers attenuates diet-induced hyperlipidemia, hepatic steatosis and insulin resistance in obesity mice by AMPK pathway." Nutrients 9.9 (2017): 959.https://doi.org/10.3390/nu9090959

18. Liu, Tongji, et al. "Improvement effect of lotus leaf flavonoids on carbon tetrachloride-induced liver injury in mice." Biomedicines 8.2 (2020): 41.https://doi.org/10.3390/biomedicines8020041

17. Qiang Zhang, Ruiyun Huo, Yibo Ma, Shuangmei Yan, Lei Yang, Fengli Chen, A novel microwave-assisted steam distillation approach for separation of essential oil from tree peony (Paeonia suffruticosa Andrews) petals: Optimization, kinetic, chemical compositio

16. Xiao-Xu Han, Ya-Ping Jiang, Ning Liu, Jing Wu, Jia-Mei Yang, Yu-Xiang Li, Miao Sun, Tao Sun, Ping Zheng, Jian-Qiang Yu, Protective effects of Astragalin on spermatogenesis in streptozotocin-induced diabetes in male mice by improving antioxidant activity a

15. 张月,唐钦悦,代娟,魏香奕,颜佳利,江岩.桑叶黄酮提取物制备及其体外抗氧化作用研究[J].中国食品添加剂,2020,31(09):47-52.

14. 姚鑫,诸炜荣,黄宏亮,曾燕如,喻卫武.掌叶覆盆子药用有效成分变异与优良种质筛选[J].中国中药杂志,2021,46(03):575-581.

13. 杜庆鑫,刘攀峰,魏艳秀,庆军,杜红岩.基于主成分与聚类分析的杜仲雄花品质综合评价[J].植物研究,2016,36(06):846-852+859.

12. 杜庆鑫, 魏艳秀, 李钦,等. 杜仲雄花生长发育动态及活性成分量变化[J]. 中草药, 2017, 048(013):2746-2751.

11. 杜庆鑫, 魏艳秀, 刘攀峰,等. 杜仲雄花主要活性成分含量的多样性[J]. 林业科学, 2017, 053(002):35-43.

10. 尹秀文, 侯成波, 陈江鹏,等. 采用在体单向肠灌流模型研究荷叶多成分整体的肠渗透性[J]. 中国中药杂志, 2017, 42(008):1525-1531.

9. 闫征, 吴寒, 黄午阳,等. 杀青工艺对蓝莓叶茶活性成分及其抗氧化性能的影响[J]. 安徽农业科学, 2019.

8. 张娟卿德刚孙宇等. 化学计量学辅助分析罗布麻中的黄酮类成分[J]. 西北药学杂志 2020 035(002):173-177.

7. 张久旭, 刘洋, 李梦薇,等. 辣木叶通便复方对小鼠通便作用的研究[J]. 中医药学报, 2019, 47(002):33-37.

6. 许佳明, 赵安琦, 谢静,等. 应用高效逆流色谱分离桑叶黄酮类化合物[J]. 分析试验室, 2019, 038(003):266-269.

5. 陈鸣, 安昌, 杨成梓,等. 基于性状描述及紫云英苷含量的野鸦椿子质量评价[J]. 海峡药学, 2019, 031(003):34-37.

4. 李梦薇, 顾文宏, 张久旭,等. 基于中心复合-响应面二次模型优化辣木叶改善睡眠复方提取工艺[J]. 辽宁中医药大学学报, 2018, 020(007):73-76.

3. 杨海洋刘洋李梦薇等. HPLC法同时测定辣木叶颗粒中异槲皮苷、紫云英苷和丹酚酸B的含量[J]. 中国药房 2019 30(09):17-20.

2. 汪慧钱巧珍王静等. HPLC法同时测定地锦草中芦丁异槲皮苷紫云英苷的含量[J]. 中华灾害救援医学 2015 003(009):509-511.

1. 郭伟滕亮万琪臻等. HPLC双波长法同时测定意大利牛舌草中3种成分的含量[J]. 西北药学杂志 2018 033(001):28-32.