Vedaprofen 维达洛芬; Quadrisol; CERM 10202; PM 150,99.81%
产品编号:Bellancom-118827| CAS NO:71109-09-6| 分子式:C19H22O2| 分子量:282.38
韦达普芬(Quadrisol)是一种COX-1选择性非甾体抗炎药(NSAID),用于抑制血清TxB2和渗出物PGE2。韦达普芬是一种大肠杆菌滑动钳(SC)抑制剂,IC50为222μM。
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Vedaprofen 维达洛芬; Quadrisol; CERM 10202; PM 150
产品介绍 | Vedaprofen (Quadrisol) 是一种 COX-1 选择性非甾体抗炎剂 (NSAID),可抑制血清中 TxB2 和渗出液中 PGE2。Vedaprofen 是一种大肠杆菌 (E. coli) 滑动钳 (SC) 抑制剂,IC50 为 222 μM。 | ||||||||||||||||||||||
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生物活性 | Vedaprofen (Quadrisol) is a COX-1 selective nonsteroidal anti-inflammatory agent (NSAID) for serum TxB2 and exudate PGE2 inhibition . Vedaprofen is a Escherichia coli (E. coli) sliding clamp (SC) inhibitor with the IC50 of 222 μM. | ||||||||||||||||||||||
体外研究 |
Vedaprofen inhibits horse serum TxB2 and horse exudate PGE2 with IC50s of 9±5 and 630±148 ng/mL, respectively. Vedaprofen inhibit the E. coli DNA polymerase III β subunit with antibacterial potency. Vedaprofen shows high E. coli SC binding affinity (Ki=131 μM). 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||||||||||||||||
体内研究 |
Pharmacokinetic parameters of vedaprofen in dogs. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||||||||||||||||
体内研究 |
Pharmacokinetic parameters of vedaprofen in dogs. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||||||||||||||||
性状 | Solid | ||||||||||||||||||||||
溶解性数据 |
In Vitro:
DMSO : 50 mg/mL (177.07 mM; ultrasonic and warming and heat to 60°C) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:
——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用;
以下溶剂前显示的百
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运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||||||||
储存方式 |
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参考文献 |
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符号 |
![]() GHS07 |
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信号词 | Warning |
危害声明 | H302 |
警示性声明 | P301 + P312 + P330 |
个人防护装备 | dust mask type N95 (US);Eyeshields;Gloves |
危险品运输编码 | NONH for all modes of transport |

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