nAChR agonist 1, 99%,nAChR agonist 1
产品编号:西域试剂-WR147107| CAS NO:1394371-75-5| 分子式:C20H18ClNO3S2| 分子量:419.940
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用途: | nAChR agonist 1 is a potent, brain-permeable, and orally efficacious positive allosteric modulator of α7 nicotinic acetylcholine receptor (α7 nAChR). nAChR agonist 1 has the EC50 of 0.32 µM in a Ca2+ mobilization assay (PNU-282987-induced, FLIPR based) in human IMR-32 neuroblastoma cells that endogenously express α7 nAChR. nAChR agonist 1 can be develpoped for the treatment of Alzheimer’s disease. |
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储存条件: | -20°C,密闭,干燥 |
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