脱氧核糖核酸酶 I|Deoxyribonuclease I (≥2,000 Kunitz units/mg)|cas:9003-98-9|西域试剂

脱氧核糖核酸酶 I,Deoxyribonuclease I (≥2,000 Kunitz units/mg)

产品编号：Sigma-D5025| CAS NO：9003-98-9| MDL NO：MFCD00130918| 分子式：Null,without related properties.| 分子量：Null,without related properties.

脱氧核糖核酸酶（DNase）是一种降解DNA的酶，它在细胞外DNA的裂解中起着关键作用，对限制炎症反应和维持体内稳定至关重要。外源性脱氧核糖核酸酶在炎症性疾病和癌症中显示出有益的作用。

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货号	价格	库存与货期
Sigma-D5025	￥780.00	杭州北京（现货）
Sigma-D5025	￥2350.00	杭州北京（现货）
Sigma-D5025	￥5380.00	杭州北京（现货）

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产品名称

脱氧核糖核酸酶 I

英文名称

Deoxyribonuclease I (≥2,000 Kunitz units/mg)

CAS编号

9003-98-9

产品描述

产品密度

100 g/mL at 20 °C

外观性状

solution (clear, colorless) | white

溶解性

Soluble in 0.15 M sodium chloride (5.0mg/L) clear.

体内研究

Deoxyribonuclease (0.1 U; i.p.; once daily for 3 days) inhibits liver metastasis, besides results in a greater prolongation of the survival period by combining surgical removal of the primary tumour mass.

XIYU has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Female BALB/c x DBA/2 mice with murine tumour L5178Y-ML cells subcutaneous injection
Dosage:	0.1 U per mouse
Administration:	Intravenous injection; 0.1 U; once daily for three days
Result:	Reduced liver weight from 2.26 to 1.55 g, affected the intensity of liver metastasis, reduced the numbers and sizes of metastatic and affected tumour cell arrest.

Animal Model:	Female BALB/c x DBA/2 mice with murine tumour and surgical removal of subcutaneous tumours
Dosage:	0.1 U per mouse
Administration:	Intravenous injection; 0.1 U; once daily for 3 days either before or after primary tumour removal
Result:	Significantly prolongated survival after tumour cell inoculation compared to the untreated group.

稳定性

1.常温常压下稳定

2.避免湿，热，高温

储存条件

-20°C密闭，避光，通风干燥处

化学品安全说明书(MSDS)

下载MSDS

个人防护装备	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
安全声明 (欧洲)	23-24/25-22
危险品运输编码	NONH for all modes of transport
WGK德国	3
RTECS号	RF0750000

脱氧核糖核酸酶 I,Deoxyribonuclease I (≥2,000 Kunitz units/mg)

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