DNase I (RNase free) DNase (RNase free)|cas:9003-98-9|西域试剂

DNase I (RNase free) DNase (RNase free)

产品编号：Bellancom-108882| CAS NO：9003-98-9| 分子式：| 分子量：

脱氧核糖核酸酶（DNase）是一种降解DNA的酶，它在细胞外DNA的裂解中起着关键作用，对限制炎症反应和维持体内稳定至关重要。外源性脱氧核糖核酸酶在炎症性疾病和癌症中显示出有益的作用。

本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用，

货号	包装	价格	库存与货期	购买量	操作
Bellancom-108882		￥200.00	杭州北京（现货）
Bellancom-108882		￥320.00	杭州北京（现货）

增值税发票√顺丰快递√订货电话：18601927057

DNase I (RNase free) DNase (RNase free)

产品介绍

DNase I (RNase free) 脱氧核糖核酸酶是一种降解 DNA 的酶，在细胞外 DNA 的裂解中起着关键作用，对限制炎症反应和维持体内平衡至关重要。外源性脱氧核糖核酸酶在炎症性疾病和癌症中发挥有益作用。

生物活性

DNase I (RNase free) is an enzyme that degrade DNA, it plays a key role in the cleavage of extracellular DNA is crucial for limiting the inflammatory response and maintaining homeostasis. Exogenous deoxyribonuclease shows beneficial effects in inflammatory diseases and cancer.

体外研究

体内研究

Deoxyribonuclease (0.1 U; i.p.; once daily for 3 days) inhibits liver metastasis, besides results in a greater prolongation of the survival period by combining surgical removal of the primary tumour mass.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Female BALB/c x DBA/2 mice with murine tumour L5178Y-ML cells subcutaneous injection
Dosage:	0.1 U per mouse
Administration:	Intravenous injection; 0.1 U; once daily for three days
Result:	Reduced liver weight from 2.26 to 1.55 g, affected the intensity of liver metastasis, reduced the numbers and sizes of metastatic and affected tumour cell arrest.

Animal Model:	Female BALB/c x DBA/2 mice with murine tumour and surgical removal of subcutaneous tumours
Dosage:	0.1 U per mouse
Administration:	Intravenous injection; 0.1 U; once daily for 3 days either before or after primary tumour removal
Result:	Significantly prolongated survival after tumour cell inoculation compared to the untreated group.

体内研究

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Female BALB/c x DBA/2 mice with murine tumour L5178Y-ML cells subcutaneous injection
Dosage:	0.1 U per mouse
Administration:	Intravenous injection; 0.1 U; once daily for three days
Result:	Reduced liver weight from 2.26 to 1.55 g, affected the intensity of liver metastasis, reduced the numbers and sizes of metastatic and affected tumour cell arrest.

Animal Model:	Female BALB/c x DBA/2 mice with murine tumour and surgical removal of subcutaneous tumours
Dosage:	0.1 U per mouse
Administration:	Intravenous injection; 0.1 U; once daily for 3 days either before or after primary tumour removal
Result:	Significantly prolongated survival after tumour cell inoculation compared to the untreated group.

性状

Solid

溶解性数据

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献

. Lauková L, et al. Deoxyribonucleases and Their Applications in Biomedicine. Biomolecules. 2020 Jul 11;10(7):1036. [Content Brief]

. Sugihara S, et al. Deoxyribonuclease treatment prevents blood-borne liver metastasis of cutaneously transplanted tumour cells in mice. Br J Cancer. 1993 Jan;67(1):66-70. [Content Brief]

化学品安全说明书(MSDS)

下载MSDS

质检证书(COA)

产品编号(Item Number)

批号(Lot Number)

个人防护装备	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
安全声明 (欧洲)	23-24/25-22
危险品运输编码	NONH for all modes of transport
WGK德国	3
RTECS号	RF0750000

DNase I (RNase free) DNase (RNase free)

DNase I (RNase free) DNase (RNase free)

化学品安全说明书(MSDS)

质检证书(COA)

在线咨询