体内研究 | Deoxyribonuclease (0.1 U; i.p.; once daily for 3 days) inhibits liver metastasis, besides results in a greater prolongation of the survival period by combining surgical removal of the primary tumour mass. XIYU has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: | Female BALB/c x DBA/2 mice with murine tumour L5178Y-ML cells subcutaneous injection | Dosage: | 0.1 U per mouse | Administration: | Intravenous injection; 0.1 U; once daily for three days | Result: | Reduced liver weight from 2.26 to 1.55 g, affected the intensity of liver metastasis, reduced the numbers and sizes of metastatic and affected tumour cell arrest. |
Animal Model: | Female BALB/c x DBA/2 mice with murine tumour and surgical removal of subcutaneous tumours | Dosage: | 0.1 U per mouse | Administration: | Intravenous injection; 0.1 U; once daily for 3 days either before or after primary tumour removal | Result: | Significantly prolongated survival after tumour cell inoculation compared to the untreated group. |
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