DNA酶, ≥2,000 Kunitz units/mg protein,DNAase

产品编号:西域试剂-WR359912| CAS NO:9003-98-9| MDL NO:MFCD00130918| 分子式:| 分子量:

脱氧核糖核酸酶(DNase)是一种降解DNA的酶,它在细胞外DNA的裂解中起着关键作用,对限制炎症反应和维持体内稳定至关重要。外源性脱氧核糖核酸酶在炎症性疾病和癌症中显示出有益的作用。

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货号 包装 价格 库存与货期 购买量 操作
西域试剂-WR359912
367.00 杭州 北京(现货)
西域试剂-WR359912
1268.00 杭州 北京(现货)
西域试剂-WR359912
2147.00 杭州 北京(现货)
西域试剂-WR359912
10393.00 杭州 北京(现货)

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产品名称DNA酶, ≥2,000 Kunitz units/mg protein
英文名称DNAase
CAS编号9003-98-9
产品描述脱氧核糖核酸酶(DNase)是一种降解DNA的酶,它在细胞外DNA的裂解中起着关键作用,对限制炎症反应和维持体内稳定至关重要。外源性脱氧核糖核酸酶在炎症性疾病和癌症中显示出有益的作用。
产品密度100 g/mL at 20 °C
外观性状solution (clear, colorless) | white
溶解性Soluble in 0.15 M sodium chloride (5.0mg/L) clear.
体内研究

Deoxyribonuclease (0.1 U; i.p.; once daily for 3 days) inhibits liver metastasis, besides results in a greater prolongation of the survival period by combining surgical removal of the primary tumour mass.

XIYU has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:Female BALB/c x DBA/2 mice with murine tumour L5178Y-ML cells subcutaneous injection
Dosage:0.1 U per mouse
Administration:Intravenous injection; 0.1 U; once daily for three days
Result:Reduced liver weight from 2.26 to 1.55 g, affected the intensity of liver metastasis, reduced the numbers and sizes of metastatic and affected tumour cell arrest.
Animal Model:Female BALB/c x DBA/2 mice with murine tumour and surgical removal of subcutaneous tumours
Dosage:0.1 U per mouse
Administration:Intravenous injection; 0.1 U; once daily for 3 days either before or after primary tumour removal
Result:Significantly prolongated survival after tumour cell inoculation compared to the untreated group.

稳定性

1.常温常压下稳定

2.避免湿,热,高温

储存条件

-20°C密闭,避光,通风干燥处

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