葛根素|cas:3681-99-0|西域试剂

葛根素,分析标准品,HPLC≥99.9%

产品编号：西域质检-TM24719| CAS NO：3681-99-0| 分子式：C₂₁H₂₀O₉| 分子量：432.378

葛根素是一种黄酮类化合物，从传统的东方药物葛根。Purarin具有潜在的抗氧化活性，可破坏CYP催化的药物代谢。一种代谢物，毛蕊异黄酮，具有细胞毒活性。葛根素预防慢性酒精中毒对空间学习记忆能力的影响主要是由于其抗炎活性和对谷氨酸和氨基丁酸平衡的调节。葛根素可能通过促进骨形成和NO/cGMP通路来预防骨质疏松，这在葛根素诱导的hBMSC增殖和成骨细胞分化中起重要作用。

本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用，

货号	包装	价格	库存与货期	购买量	操作
西域质检-TM24719		￥450.00	杭州北京（现货）
西域质检-TM24719		￥120.00	杭州北京（现货）

增值税发票√顺丰快递√订货电话：18601927057

葛根素

Reference Material

This certificate is designed in accordance with ISO 17034 and ISO Guide 31. This reference material (RM) was designed,produced and verified in accordance with ISO/IEC 17025, ISO 17034 and a registered quality management system ISO 9001.

Product Name(产品名称) Puerarin(葛根素)

Product Code(产品编号) 78078-50mg

Lot Number(产品批号) 23030088

CAS No. 3681-99-0

Mol. Weight(分子量) 416.38

Mol. Formula(分子式) C₂₁H₂₀O₉

Melting Point(熔点) N/A

Expiry Date(失效日期) 2025-Mar-06

Boiling point(沸点) N/A

Appearance(外观) White to Off-White Solid
(白色固体)

Storage Temp(存储条件) (2~8)℃,dark
冷藏(2~8)℃避光

C E R T I F I E D

Purity

99.9%

C E R T I F I E D

Expanded Uncertainty (U)

0.8%

Uncertainty

The certified value(s) and uncertainty(ies) are determined in accordance with ISO 17034 with an 95% confidence level(k=2). Uncertainty is based on the Total Combined Uncertainty, including uncertainties of characterisation, homogeneity and stability testing. Stability values are based on real evidence opposed to simulation.

Traceability

The balances used for gravimetric measurements are calibrated with weights traceable to the national standards. The calibration of the balances is verified annually by an external accredited calibration service. This analysis method has been verified using an approach consistent with ISO 17034:2016 & ISO 17025:2017.

CERTIFICATE ON	QC SIGNATURE
2023-Mar-07		RM Release

Method of Identification

HPLC

Method of Identification

HPLC

Intended Use

This RM is intended for use in a laboratory as a calibration and quality control standard or in method development for analytical techniques.

Storage

This reference material meets the specification stated in this certificate until the expiry date, provided it is stored unopened at the recommended temperature here in. If storage after opening is necessary, the RM should be tightly closed and kept from light and moisture.

Hazards

Read Material Safety Data Sheet (MSDS) and understand any potential hazard(s) prior to the use of this product. All chemicals should be considered potentially hazardous in nature and should only be handled by qualified personnel using established good laboratory practices.

Homogeneity

Random replicate samples of the final packaged RM have been analysed to prove homogeneity compliant with ISO 17034.

Instructions for use

It is recommended to use 1 mg as the minimum sample size and if less material is used, to increase the certified uncertainty by a factor of two for half sample and four for a quarter of sample.Visit the support section of our website technology videos and frequently asked questions.

化学品安全说明书(MSDS)

下载MSDS

质检证书(COA)

个人防护装备	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
危害码 (欧洲)	F,C
风险声明 (欧洲)	R11
安全声明 (欧洲)	22-24/25-45-36/37/39-26-16
危险品运输编码	NONH for all modes of transport
WGK德国	3
RTECS号	UO5216000
海关编码	2932999099

1. 物质的识别

产品名：	Puerarin
CAS号：	3681-99-0
制造商/供应商：	西域试剂网站：www.hzbp.cn 邮件：13911702513@139.com

2. 合成/成分数据

产品名：	Puerarin
分子式：	C21H20O9
分子量：	416.38

3. 急救措施

吸入后：	如果吸入，移至空气新鲜处，如果呼吸困难，给输氧，如呼吸停止，给予人工呼吸。
皮肤接触后：	用大量的水冲洗，移除污染的衣服和鞋子。
眼睛接触后：	检查并取下隐形眼镜，并用大量的水冲洗；呼叫医生。
吞食后：	如果吞食，用大量纯净水漱口；呼叫医生。

4. 消防措施

适当的灭火剂：	雾状水，二氧化碳，干粉或泡沫。
防护设备：	穿戴自给式呼吸器和防护服，以防止与皮肤和眼睛接触。

5. 泄漏应急处理

安全防范措施：	封锁泄漏区域；穿戴自给式呼吸器，防护服和厚橡胶手套。
清洁/收集措施：	使用液体粘合原料（硅藻土，通用粘合剂）吸取精细粉末；使用酒精擦洗表面和设备除去污渍；根据第11条处理被污染的材料。

6. 处理和储存

安全处理说明：	避免吸入和接触皮肤，眼睛及衣物；材料可能略微具有刺激性。
储存：	粉末型式 -20°C 3年；4°C 2年溶于溶剂 -80°C 6个月；-20°C 1个月

7. 接触控制和个人防护

呼吸设备：	NIOSH / MSHA认可的呼吸器。
双手保护：	耐化学腐蚀的橡胶手套。
眼睛防护：	化学安全护目镜。

8. 稳定性和反应活性

稳定性：	按照说明存储是稳定的；避免强氧化剂。
热分解/其他要避免的情况：	避免光和热。

9. 毒性资料

急性毒性：	无可用资料。
主要刺激性影响：	无可用资料。
在皮肤上：	无可用资料。
对眼睛：	无可用资料；可能具有刺激性。

10. 生态资料

一般注意事项：

无可用资料。

11. 废弃处置

按照所在国家，省份，县市和地方的法规处置。

12. 运输信息

正确的运输名称：	无
非危险品运输：	这种物质被视为非危险品运输。

13. 法规信息

尚未有针对此产品作出的化学安全性评估。

14. 其他信息

1242241-66-2

~71%

3681-99-0

文献：Kato, Eisuke; Kawabata, Jun Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 15 p. 4333 - 4336

1029605-74-0

~76%

3681-99-0

文献：Lee; Ji; Zhang Journal of Labelled Compounds and Radiopharmaceuticals, 2007 , vol. 50, # 8 p. 702 - 705

69667-95-4

3681-99-0

文献：Lee, David Y. W.; Zhang, Wu-Yan; Karnati, Vishnu Vardhan R. Tetrahedron Letters, 2003 , vol. 44, # 36 p. 6857 - 6859

147899-32-9

3681-99-0

文献：Park; Hakamatsuka; Noguchi; Sankawa; Ebizuka Chemical and Pharmaceutical Bulletin, 1992 , vol. 40, # 7 p. 1978 - 1980

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1. 崔灵张丽姝陈萌萌等. HPLC法同时测定知葛胶囊中葛根素、马钱苷、芒果苷以及芦丁的含量[J]. 沈阳药科大学学报 2018(7).

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